Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.62 |
| ▸ | MMP12 | P39900 | 4/20 | 0.62 |
| ▸ | MMP9 | P14780 | 3/20 | 0.62 |
| ▸ | MMP8 | P22894 | 3/20 | 0.60 |
| ▸ | MMP13 | P45452 | 3/20 | 0.60 |
| ▸ | MMP14 | P50281 | 3/20 | 0.60 |
| ▸ | MMP16 | P51512 | 3/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP3 | P08254 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941492 | 0.86 | MMP2 (0.58) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL7596724 | 0.86 | FFAR1 (0.52) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL10713781 | 0.85 | MMP2 (0.56) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL3738351 | 0.84 | HSD17B10 (0.64) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL5961842 | 0.83 | PTGS1 (0.59) | MMP2MMP12MMP9MMP8MMP13 | |
| Ethane SCHEMBL28588588 | 0.83 | PTGS1 (0.57) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL9890648 | 0.83 | HSD17B10 (0.62) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL538512 | 0.82 | KMT2A (0.60) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL3738754 | 0.81 | FFAR1 (0.53) | MMP2MMP12MMP9MMP8MMP13 | |
| SCHEMBL7176319 | 0.81 | EGFR (0.55) | LPAR1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| WO-2005092062-A2 | COMPOUNDS FOR NEURODEGENERATIVE DISORDERS | MYRIAD GENETICS, INC. (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | MMP2 3634/4885MMP12 3650/4885MMP9 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.