Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP12 | P39900 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP14 | P50281 | 3/20 | 0.49 |
| ▸ | MMP16 | P51512 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738351 | 0.92 | HSD17B10 (0.64) | HSD17B10PTGS1MMP2MMP12KDM4E | |
| SCHEMBL3735319 | 0.88 | HSD17B10 (0.59) | HSD17B10PTGS1MMP2MMP12KDM4E | |
| SCHEMBL9890726 | 0.88 | PLA2G10 (0.52) | HSD17B10KDM4EBACE1SMN1; SMN2MAPT | |
| SCHEMBL11889771 | 0.87 | HSD17B10 (0.55) | HSD17B10MMP2MMP12KDM4EMMP9 | |
| SCHEMBL3736235 | 0.87 | HSD17B10 (0.57) | HSD17B10PTGS1KDM4EAKR1C3AKR1C2 | |
| SCHEMBL3738751 | 0.87 | HSD17B10 (0.57) | HSD17B10PTGS1MMP2MMP12KDM4E | |
| SCHEMBL3737508 | 0.86 | CYP11B2 (0.55) | HSD17B10KDM4E | |
| SCHEMBL4961133 | 0.83 | PTPN1 (0.50) | KDM4EBACE1SMN1; SMN2MAPTTAS1R3 | |
| SCHEMBL27821291 | 0.83 | BAZ2B (0.53) | HSD17B10KDM4EBACE1SMN1; SMN2MAPT | |
| SCHEMBL5235960 | 0.83 | HSD17B10 (0.54) | HSD17B10PTGS1MMP2MMP12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | HRH3, KCNH3, BRPF3 | HSD17B10 1303/4885PTGS1 2007/4885MMP2 1085/4885 |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | HRH3, KCNH3, BRPF3 | HSD17B10 1303/4885PTGS1 2007/4885MMP2 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.