Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205163 | 0.76 | TAAR1 (0.44) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL4729505 | 0.75 | TAAR1 (0.54) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL4218065 | 0.74 | CYP2C19 (0.45) | TAAR1ADRA2AADRA2BADRA2CTSHR | |
| Ammonia Solution, Strong SCHEMBL28852825 | 0.73 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL4210706 | 0.73 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL1866420 | 0.73 | CYP2C19 (0.47) | TAAR1ADRA2AADRA2BADRA2CCYP2C19 | |
| SCHEMBL27963007 | 0.69 | ALDH1A1 (0.40) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL23094084 | 0.69 | TAAR1 (0.50) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL5310132 | 0.69 | KMT2A (0.50) | TAAR1ADRA2AADRA2BADRA2CPOLB | |
| SCHEMBL9685393 | 0.69 | KMT2A (0.50) | TAAR1ADRA2AADRA2BADRA2CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131502-A1 | Biologically active compounds | QUIBELL MARTIN | 2009-05-21 | — | — | US | disclosed |
| US-20090131502-A1 | Biologically active compounds | QUIBELL MARTIN | 2009-05-21 | — | — | US | disclosed |
| US-20090131502-A1 | Biologically active compounds | QUIBELL MARTIN | 2009-05-21 | — | — | US | disclosed |
| WO-2007023281-A2 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007023281-A2 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131502-A1 | Biologically active compounds | COLGALT1, SOST, COL1A1 | TAAR1 4787/4885ADRA2A 3869/4885ADRA2B 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.