Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.95 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.95 |
| ▸ | DRD2 | P14416 | 8/20 | 0.95 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526989 | 0.97 | ADRB2 (1.00) | ADRB2ADRB1DRD2ADRA1DDRD3 | |
| Trifluoroacetic Acid SCHEMBL4522481 | 0.92 | ADRB2 (0.90) | ADRB2ADRB1DRD2ADRA1DDRD3 | |
| SCHEMBL4533977 | 0.91 | ADRB2 (1.00) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL5126179 | 0.91 | ADRB2 (0.87) | ADRB2ADRB1DRD2ADRA1DDRD3 | |
| SCHEMBL5120384 | 0.91 | ADRB2 (0.87) | ADRB2ADRB1DRD2ADRA1DDRD3 | |
| Hydrochloric Acid SCHEMBL4521142 | 0.91 | ADRB2 (0.98) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL4519445 | 0.90 | ADRB2 (1.00) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL4525733 | 0.90 | ADRB2 (1.00) | ADRB2ADRB1DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL4525708 | 0.89 | ADRB2 (0.98) | ADRB2ADRB1DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL4528763 | 0.89 | ADRB2 (0.98) | ADRB2ADRB1DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203753-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | US | claimed |
| US-20090203753-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | US | disclosed |
| US-20090203753-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | US | disclosed |
| US-20090203753-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | US | disclosed |
| WO-2007027133-A1 | 7-(2-AMINO-1-HYDROXY-ETHYL)-4-HYDROXYBENZOTHIAZOL-2(3H)-ONE-DERIVATIVES AS β2 ADRENOCEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203753-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ADRB2, ADRB1, ADRA1D | ADRB2 1/4885ADRB1 2/4885DRD2 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.