Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972073 | 0.81 | MAPK1 (0.48) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4230064 | 0.81 | KMT2A (0.40) | HTTKMT2AMAPTSMN1; SMN2FNTA | |
| SCHEMBL4225404 | 0.80 | HTT (0.47) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL4230170 | 0.77 | HTT (0.38) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL4225555 | 0.75 | HTT (0.40) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL2982074 | 0.71 | ALDH1A1 (0.49) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL27305848 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13203248 | 0.67 | DAPK3 (0.51) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13203355 | 0.66 | LMNA (0.43) | HTTMEN1KMT2AMAPTLMNA | |
| SCHEMBL4221626 | 0.66 | HTT (0.48) | HTTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2093226-A1 | New aminoindolizines, tinctorial composition comprising an aminoindolizine, methods and uses | L'Oreal (FR) | 2009-08-26 | — | — | EP | disclosed |