SCHEMBL4220076

SCHEMBL4220076

F[B-](F)(F)F.F[B-](F)(F)F.N#[N+]c1ccc(CCN)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 10/20 0.48
HTR2A P28223 3/20 0.43
CYP2A6 P11509 2/20 0.43
CYP1A2 P05177 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43
SLC6A2 P23975 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTR3A P46098 1/20 0.43
BACE1 P56817 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAOB P27338 3/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LOXL2 Q9Y4K0 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
F2 P00734 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2232788 1.00 TAAR1 (0.48) TAAR1HTR2ACYP2A6CYP1A2KDM4E
SCHEMBL4220077 1.00 TAAR1 (0.48) TAAR1HTR2ACYP2A6CYP1A2KDM4E
SCHEMBL1535981 0.92 TAAR1 (0.50) TAAR1HTR2ACYP2A6CYP1A2KDM4E
SCHEMBL23356017 0.83 LOXL2 (0.44) TAAR1CYP2A6LOXL2
SCHEMBL2232785 0.82
SCHEMBL1792657 0.80 CA2 (0.45) KDM4EALDH1A1BACE1TDP1TSHR
SCHEMBL4739789 0.80 TDP1 (0.41) KMT2ATDP1
SCHEMBL6870559 0.79 ALDH1A1 (0.38) ALDH1A1TDP1SMN1; SMN2TP53TSHR
SCHEMBL5370217 0.78
SCHEMBL5380526 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8298946-B2 Method of selective coating of a composite surface production of microelectronic interconnections using said method and integrated circuits ALCHIMER (FR) 2012-10-30 US claimed
US-20090095507-A1 METHOD OF SELECTIVE COATING OF A COMPOSITE SURFACE PRODUCTION OF MICROELECTRONIC INTERCONNECTIONS USING SAID METHOD AND INTEGRATED CIRCUITS ALCHIMER (FR) 2009-04-16 US claimed
US-8298946-B2 Method of selective coating of a composite surface production of microelectronic interconnections using said method and integrated circuits ALCHIMER (FR) 2012-10-30 US disclosed
US-20090095507-A1 METHOD OF SELECTIVE COATING OF A COMPOSITE SURFACE PRODUCTION OF MICROELECTRONIC INTERCONNECTIONS USING SAID METHOD AND INTEGRATED CIRCUITS ALCHIMER (FR) 2009-04-16 US disclosed