Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5972444 | 0.91 | MEN1 (0.35) | MAOAMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7131959 | 0.87 | BRD4 (0.36) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL5972535 | 0.84 | MEN1 (0.36) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL27279407 | 0.83 | MEN1 (0.35) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28567301 | 0.82 | CAMKK2 (0.42) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL27919288 | 0.81 | CAMKK2 (0.41) | MEN1KMT2AHPGDKDM4ELMNA | |
| SCHEMBL2639056 | 0.81 | KCNH2 (0.38) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL10615615 | 0.80 | ALDH1A1 (0.35) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28768435 | 0.79 | MAPT (0.39) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL28549794 | 0.79 | HRH1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009107859-A2 | POLYMER NANOPARTICLE AND CONTRAST AGENT FOR OPTICAL MOLECULAR IMAGING | KYOTO UNIVERSITY (JP) | 2009-09-03 | — | — | WO | disclosed |