Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.78 |
| ▸ | CTSS | P25774 | 3/20 | 0.59 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221898 | 1.00 | CTSK (0.78) | CTSKCTSSHPGDSCCR1CTSV | |
| SCHEMBL5941681 | 1.00 | CTSK (0.78) | CTSKCTSSHPGDSCCR1CTSV | |
| SCHEMBL4221901 | 1.00 | CTSK (0.78) | CTSKCTSSHPGDSCCR1CTSV | |
| SCHEMBL4042499 | 0.88 | CTSK (0.74) | CTSKCTSSCCR1 | |
| SCHEMBL4039102 | 0.88 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL5941421 | 0.88 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4210236 | 0.88 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4210233 | 0.88 | CTSK (1.00) | CTSKCTSSCCR1CTSVCTSL | |
| SCHEMBL4044153 | 0.87 | CTSK (0.70) | CTSKCTSSHPGDSCCR1CTSV | |
| SCHEMBL8349299 | 0.87 | CTSK (0.70) | CTSKCTSSHPGDSCCR1CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |