Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283212 | 0.91 | MAPK1 (0.60) | SLC22A12CYP2C9PTPN1EYA3MAPK1 | |
| SCHEMBL5020569 | 0.85 | SLC22A12 (0.68) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| SCHEMBL15488929 | 0.85 | SLC22A12 (0.58) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| SCHEMBL5225391 | 0.85 | NR1H4 (0.60) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| SCHEMBL9486161 | 0.84 | HTT (0.62) | SLC22A12CYP2C9EYA3MAPK1HTT | |
| SCHEMBL12074771 | 0.84 | SLC22A12 (0.57) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| SCHEMBL5672649 | 0.84 | SLC22A12 (0.57) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| SCHEMBL11823752 | 0.84 | SLC22A12 (0.57) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| Hydrochloric Acid SCHEMBL27860354 | 0.83 | SLC22A12 (0.56) | SLC22A12CYP2C9PTPN1EYA3ESR1 | |
| SCHEMBL4567254 | 0.82 | KDM5A (0.58) | ESR1PGRCHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674121-B2 | Process for the production of benzofurans | SANOFI (FR) | 2014-03-18 | — | — | US | disclosed |
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | SANOFI (FR) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065411-A1 | PROCESS FOR THE PRODUCTION OF BENZOFURANS | CYP2F1, CYP2B6, CYP4F2 | SLC22A12 3257/4885CYP2C9 50/4885PTPN1 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.