Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.68 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020570 | 0.91 | EYA3 (0.77) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL15488929 | 0.89 | SLC22A12 (0.58) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL5225391 | 0.89 | NR1H4 (0.60) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL1287500 | 0.88 | SLC22A12 (0.86) | SLC22A12EYA3CYP2C9NPC1MAPT | |
| SCHEMBL5672649 | 0.88 | SLC22A12 (0.57) | SLC22A12EYA3PTPN1CYP2C9ESR1 | |
| SCHEMBL12074771 | 0.88 | SLC22A12 (0.57) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL11823752 | 0.88 | SLC22A12 (0.57) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| Hydrochloric Acid SCHEMBL27860354 | 0.87 | SLC22A12 (0.56) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL422204 | 0.85 | SLC22A12 (0.54) | SLC22A12EYA3PTPN1CYP2C9NR1H4 | |
| SCHEMBL5227728 | 0.85 | SLC22A12 (0.54) | SLC22A12EYA3PTPN1CYP2C9NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062918-A1 | PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES | LEK PHARMACEUTICALS D.D. (SI) | 2012-05-18 | — | — | WO | disclosed |