SCHEMBL4222152

SCHEMBL4222152

[O]Sc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 7/20 0.52
HSD17B10 Q99714 2/20 0.52
ACHE P22303 1/20 0.52
MAPK1 P28482 2/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.49
CES1 P23141 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
PKM P14618 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
CA12 O43570 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4163474 0.82 MAPT (0.79) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL223594 0.82 MEN1 (0.59) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL3328543 0.82 MAPT (0.79) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL22567 0.81 ALDH1A1 (0.72) MEN1KMT2AALDH1A1HSD17B10ACHE
SCHEMBL27909482 0.81 ALDH1A1 (0.72) MEN1KMT2AALDH1A1HSD17B10ACHE
SCHEMBL10336979 0.80 MAPT (0.57) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL8934655 0.80 MAPT (0.76) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL8934649 0.80 MAPT (0.76) MAPTMEN1KMT2AALDH1A1HSD17B10
Fluoride SCHEMBL29135589 0.80 MAPT (0.76) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL856512 0.78 MAPT (0.55) MAPTMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1995254-B1 METHOD OF PRODUCING PEPTIDES KANEKA CORP (JP) 2019-04-03 EP disclosed
US-9346850-B2 Method of producing peptide KANEKA CORPORATION (JP) 2016-05-24 US disclosed
US-20140288268-A1 METHOD OF PRODUCING PEPTIDE KANEKA CORPORATION (JP) 2014-09-25 US disclosed
US-8716439-B2 Method of producing peptide KANEKA CORPORATION (JP) 2014-05-06 US disclosed
US-20090069538-A1 Method of Producing Peptide KANEKA CORPORATION (JP) 2009-03-12 US disclosed
EP-1995254-A1 METHOD OF PRODUCING PEPTIDE Kaneka Corporation (JP) 2008-11-26 EP disclosed