SCHEMBL856512

SCHEMBL856512

O=[N+]([O-])c1ccc(SCl)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 3/20 0.50
ACHE P22303 1/20 0.50
LMNA P02545 1/20 0.48
CES1 P23141 1/20 0.46
IDO1 P14902 1/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
LOXL2 Q9Y4K0 1/20 0.45
CA12 O43570 1/20 0.45
CA3 P07451 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3328543 0.80 MAPT (0.79) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL223594 0.80 MEN1 (0.59) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL4163474 0.80 MAPT (0.79) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL22567 0.79 ALDH1A1 (0.72) MEN1KMT2AALDH1A1HSD17B10ACHE
SCHEMBL27909482 0.79 ALDH1A1 (0.72) MEN1KMT2AALDH1A1HSD17B10ACHE
SCHEMBL10336979 0.78 MAPT (0.57) MAPTMEN1KMT2AALDH1A1HSD17B10
Fluoride SCHEMBL29135589 0.78 MAPT (0.76) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL8934649 0.78 MAPT (0.76) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL8934655 0.78 MAPT (0.76) MAPTMEN1KMT2AALDH1A1HSD17B10
SCHEMBL4222152 0.78 MAPT (0.57) MAPTMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410114-B 4-nitrobenzene sulfur chlorine amino protecting group and preparation method thereof 南开大学 2024-02-27 CN claimed
CN-116410114-A 4-nitrobenzene sulfur chlorine amino protecting group and preparation method thereof 南开大学 2023-07-11 CN claimed
EP-1289561-A2 LIGAND CONJUGATES AND METHODS FOR PREPARING SAME NATIONAL UNIVERSITY OF SINGAPORE (SG) 2003-03-12 EP claimed
WO-2001054731-A2 LIGAND CONJUGATES AND METHODS FOR PREPARING SAME NATIONAL UNIVERSITY OF SINGAPORE (SG) 2001-08-02 WO claimed
JP-5286980-A None JP disclosed
CN-118978463-A Synthesis method of 9-aryl-10-sulfoxide phenanthrene compound 淮北师范大学 2024-11-19 CN disclosed
WO-2023034812-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2023-03-09 WO disclosed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
US-11292968-B2 Sulfenamides as flame retardants SONGWON INTERNATIONAL AG (CH) 2022-04-05 US disclosed
CN-110872384-B Flame retardant composition, use thereof and method for the production thereof 松原国际股份有限公司 2022-02-25 CN disclosed
US-20210163408-A1 METHOD FOR PREPARING A POLYFLUORINATED COMPOUND ETH ZURICH (CH) 2021-06-03 US disclosed
EP-3802488-A1 METHOD FOR PREPARING A POLYFLUORINATED COMPOUND ETH Zurich (CH) 2021-04-14 EP disclosed
EP-0013414-A2 Urea derivatives, process for their preparation and their use as insecticides CELAMERCK GmbH & Co. KG (DE) 1980-07-23 EP disclosed
US-4196152-A Algicidal and fungicidal 1-halo-2-substituted-thioethyl sulfones, 2-substituted-thiovinyl sulfones, and 1,2-dihalothioethyl sulfones CHEVRON RESEARCH COMPANY (US) 1980-04-01 US disclosed
US-4104264-A REACTING FREE HYDROXYL GROUPS WITH A SULFUR COMPOUND AIR PRODUCTS & CHEMICALS, INC. (US) 1978-08-01 US disclosed
US-4061629-A 6-Amino-6-arylthio penicillanic acids and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1977-12-06 US disclosed
US-4029669-A 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1977-06-14 US disclosed
US-3980787-A DIURETIC AND ANTIHYPERTENSIVE AGENTS AMERICAN HOECHST CORPORATION (US) 1976-09-14 US disclosed
US-3965093-A 6-Arylthio penicillanic acid and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1976-06-22 US disclosed
US-3943154-A PLANT AND ANIMAL GROWTH REGULATORS SANITIZED INCORPORATED (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11292968-B2 Sulfenamides as flame retardants STS, TST, PFAS MAPT 1238/4885MEN1 4418/4885KMT2A 918/4885
US-20210163408-A1 METHOD FOR PREPARING A POLYFLUORINATED COMPOUND AFF4, AR, AFF2 MAPT 4324/4885MEN1 2456/4885KMT2A 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.