Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.84 |
| ▸ | HTT | P42858 | 3/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375687 | 0.90 | MAPT (0.96) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL15106689 | 0.88 | MAPT (0.65) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL3224251 | 0.87 | NPC1 (0.81) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL4049476 | 0.87 | MAPT (0.64) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL30205105 | 0.87 | NPC1 (0.81) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL12228747 | 0.86 | MAPT (0.82) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL29229968 | 0.85 | NPC1 (0.69) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL23409046 | 0.85 | MAPT (0.61) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL5990725 | 0.85 | MAPT (0.61) | MAPTHTTNPSR1ALDH1A1POLB | |
| SCHEMBL30070804 | 0.85 | MAPT (0.61) | MAPTHTTNPSR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2803069-B1 | HOLOGRAPHIC RECORDING MEDIUM AND METHOD OF MAKING HOLOGRAPHIC RECORDING MEDIUM | SABIC INNOVATIVE PLASTICS IP (NL) | 2016-02-03 | — | — | EP | disclosed |
| US-8663873-B2 | Holographic recording medium and method of recording a hologram | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-04 | — | — | US | disclosed |
| US-8663873-B2 | Holographic recording medium and method of recording a hologram | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-04 | — | — | US | disclosed |
| WO-2013106138-A1 | HOLOGRAPHIC RECORDING MEDIUM AND METHOD OF MAKING HOLOGRAPHIC RECORDING MEDIUM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-07-18 | — | — | WO | disclosed |
| US-20130183608-A1 | HOLOGRAPHIC RECORDING MEDIUM AND METHOD OF MAKING HOLOGRAPHIC RECORDING MEDIUM | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-07-18 | — | — | US | disclosed |
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | MERCK SHARP & DOHME CORP. | 2009-08-06 | — | — | US | disclosed |
| EP-1858513-A4 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080274425-A1 | Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080182202-A1 | Planographic printing plate material and resin used therein | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-31 | — | — | US | disclosed |
| US-20080160445-A1 | Planographic printing plate material, and method of preparing planographic printing plate employing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080131812-A1 | Resin for printing plate material and lithographic printing plate material by use thereof | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1858513-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006098912-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2006-09-21 | — | — | WO | disclosed |
| EP-0911153-B1 | Image forming method | KONISHIROKU PHOTO IND (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6174646-B1 | IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION | KONICA CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0911153-A1 | Image forming method | KONICA CORPORATION (JP) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197883-A1 | Diphenyl Substituted Cycloalkanes, Compositions Containing Such Compounds and Methods Of Use | ALOX5, LTC4S, ALOX15B | MAPT 4739/4885HTT 3792/4885NPSR1 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.