Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386711 | 0.88 | EPHX2 (0.49) | HDAC1HDAC3HDAC8CYP1A2HDAC2 | |
| SCHEMBL4233200 | 0.88 | HDAC3 (0.41) | HDAC1HDAC3HDAC8CYP1A2PIK3CA | |
| SCHEMBL4224300 | 0.87 | RAB9A (0.41) | RAB9ANPC1CYP1A2DGAT1LMNA | |
| SCHEMBL4233251 | 0.87 | HDAC1 (0.39) | HDAC1HDAC3HDAC8CYP1A2PIK3CA | |
| SCHEMBL4224540 | 0.86 | EPHX2 (0.48) | HDAC1HDAC3HDAC8CYP1A2HDAC2 | |
| SCHEMBL4364256 | 0.86 | EPHX2 (0.44) | HDAC1LMNAMAPT | |
| SCHEMBL4228671 | 0.85 | HDAC1 (0.41) | HDAC1HDAC3HDAC8CYP1A2HDAC2 | |
| SCHEMBL4222628 | 0.84 | HDAC1 (0.38) | HDAC1HDAC3HDAC8CYP1A2PIK3CA | |
| SCHEMBL4229364 | 0.84 | HDAC1 (0.40) | HDAC1HDAC3HDAC8HDAC2HDAC10 | |
| SCHEMBL4234525 | 0.83 | HDAC1 (0.41) | HDAC1HDAC3HDAC8HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |