Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.78 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223101 | 1.00 | CTSK (0.78) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL5942130 | 1.00 | CTSK (0.78) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL5942134 | 1.00 | CTSK (0.78) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL4215063 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL4043209 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL4215058 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL5942270 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL5941303 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL4223964 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL | |
| SCHEMBL5941302 | 0.96 | CTSK (0.76) | CTSKCTSSPOLBCCR1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488724-B2 | 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors | SOUTHERN METHODIST UNIVERSITY FOUNDATION FOR RESEARCH (US) | 2009-02-10 | — | — | US | disclosed |
| US-20060074065-A1 | 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors | ALAMX LLC | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074065-A1 | 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors | CMBL, CES2, BCHE | CTSK 637/4885CTSS 138/4885POLB 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.