Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Pelargonidin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | CD38 | P28907 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422338 | 0.81 | POLB (0.80) | POLBCTDSP1HSP90AA1MAPTKDM4E | |
| SCHEMBL422339 | 0.81 | POLB (0.80) | POLBCTDSP1HSP90AA1MAPTKDM4E | |
| Galioside SCHEMBL29431810 | 0.74 | POLB (1.00) | POLBCTDSP1MAPTJUN | |
| Gardenoside SCHEMBL306407 | 0.74 | POLB (1.00) | POLBCTDSP1MAPTJUN | |
| SCHEMBL29426021 | 0.73 | POLB (0.69) | POLBCTDSP1DPP4HSP90AA1AKR1B1 | |
| SCHEMBL29751499 | 0.72 | POLB (0.57) | POLBCTDSP1DPP4HSP90AA1MAPT | |
| Fluorouracil SCHEMBL23495449 | 0.72 | POLB (0.63) | POLBCTDSP1HSP90AA1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL29991538 | 0.71 | CD38 (0.83) | CD38DPP4F2GLO1OR51E2 | |
| Hydrochloric Acid SCHEMBL316939 | 0.71 | CD38 (0.83) | CD38DPP4F2GLO1OR51E2 | |
| Hydrochloric Acid SCHEMBL3437710 | 0.70 | CD38 (0.82) | CD38DPP4F2GLO1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006083666-A1 | ANTI-INFLAMMATORY SUPPLEMENT COMPOSITIONS AND REGIMENS TO REDUCE CARDIOVASCULAR DISEASE RISKS | A.M. TODD COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |