SCHEMBL4223426

SCHEMBL4223426

CCCCCc1cc(C2=CCC(c3ccc(O)cc3)CC2)ccc1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 0.40
TYR P14679 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 2/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX5 P09917 2/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
RBP1 P09455 1/20 0.35
ESR1 P03372 7/20 0.35
GPR55 Q9Y2T6 1/20 0.35
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4216580 0.99 TYR (0.41) ESR2TYRMEN1MAPTKMT2A
SCHEMBL4227424 0.99 TYR (0.41) ESR2TYRMEN1MAPTKMT2A
SCHEMBL4223459 0.99 TYR (0.41) ESR2TYRMEN1MAPTKMT2A
SCHEMBL3809673 0.97 ESR2 (0.41) ESR2TYRMEN1MAPTKMT2A
SCHEMBL3808060 0.92 ESR2 (0.43) ESR2CYP3A4ALOX5ESR1
SCHEMBL2719243 0.87 ESR2 (0.45) ESR2CYP3A4ESR1
SCHEMBL2721993 0.83 ESR2 (0.36) ESR2
SCHEMBL3816888 0.82 ESR2 (0.42) ESR2CYP3A4ESR1
SCHEMBL4220078 0.81 CNR2 (0.38) ESR2
SCHEMBL5388046 0.80 ALOX5 (0.39) ESR2TYRMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054669-A1 Process For Producing Epoxy Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054669-A1 Process For Producing Epoxy Compound RER1, AR, CYP1A1 ESR2 4/4885TYR 1415/4885MEN1 1841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.