Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | QDPR | P09417 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387165 | 0.92 | ALOX5 (0.47) | ALOX5ESR2HSD17B1ESR1QDPR | |
| SCHEMBL5382437 | 0.86 | HSD17B1 (0.46) | ALOX5ESR2HSD17B1ESR1QDPR | |
| SCHEMBL3809673 | 0.83 | ESR2 (0.41) | ALOX5TYRESR2ESR1MEN1 | |
| SCHEMBL5389243 | 0.80 | GABRA1 (0.45) | ESR2HSD17B1QDPR | |
| SCHEMBL4223426 | 0.80 | ESR2 (0.40) | ALOX5TYRESR2ESR1MEN1 | |
| SCHEMBL4223459 | 0.79 | TYR (0.41) | ALOX5TYRESR2ESR1MEN1 | |
| SCHEMBL4216580 | 0.79 | TYR (0.41) | ALOX5TYRESR2ESR1MEN1 | |
| SCHEMBL4227424 | 0.79 | TYR (0.41) | ALOX5TYRESR2ESR1MEN1 | |
| SCHEMBL4226123 | 0.77 | TYR (0.47) | ALOX5TYRESR2HSD17B1ESR1 | |
| SCHEMBL17709428 | 0.76 | TYR (0.55) | ALOX5TYRESR2HSD17B1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196232-B2 | 4,4′-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-03-27 | — | — | US | claimed |
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-06-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060129001-A1 | Novel 4,4'-dihydroxyphenyl bicyclohexenes | DBF4, DCUN1D4, SDC4 | ALOX5 2726/4885TYR 660/4885ESR2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.