Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223674 | 0.69 | CNR1 (0.33) | ALDH1A1GFERRXFP1METAP2 | |
| SCHEMBL4214908 | 0.60 | NR1I2 (0.33) | — | |
| SCHEMBL4210571 | 0.59 | MAP3K12 (0.33) | METAP2 | |
| SCHEMBL11251103 | 0.57 | ALDH1A1 (0.41) | CXCR2ALDH1A1GFERRXFP1KCNQ3 | |
| SCHEMBL11846106 | 0.56 | CCNA2 (0.31) | ALDH1A1 | |
| SCHEMBL31617117 | 0.55 | AURKA (0.36) | ALDH1A1METAP2 | |
| SCHEMBL31617121 | 0.55 | AURKA (0.36) | ALDH1A1METAP2 | |
| SCHEMBL23778668 | 0.55 | ALDH1A1 (0.42) | CXCR2ALDH1A1GFERRXFP1 | |
| SCHEMBL20875438 | 0.54 | MEN1 (0.34) | ALDH1A1METAP2 | |
| SCHEMBL11260682 | 0.54 | DGAT1 (0.40) | ALDH1A1GFERRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494996-B2 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2009-02-24 | — | — | US | disclosed |
| US-20040242580-A1 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones and their use as fungicides and insecticides | KELLY MARTHA JEAN (US) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242580-A1 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones and their use as fungicides and insecticides | DDT, CYP4B1, CYP4X1 | CXCR2 3489/4885ALDH1A1 255/4885GFER 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.