Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892218 | 0.86 | RET (0.51) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL1893757 | 0.84 | MAPT (0.50) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL1893755 | 0.84 | MAPT (0.50) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL15251881 | 0.80 | FFAR1 (0.55) | MAPTNPC1RAB9AMAOBHPGD | |
| SCHEMBL13829409 | 0.78 | MAPT (0.51) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL11256026 | 0.75 | MAPT (0.51) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL1772053 | 0.74 | CYP3A4 (0.50) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL1886532 | 0.74 | CYP3A4 (0.45) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL1886531 | 0.74 | CYP3A4 (0.45) | MAPTNPC1RAB9ACYP19A1MAOB | |
| SCHEMBL28902155 | 0.74 | TSHR (0.52) | MAPTTP53RETKDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108392-A2 | CATALYTIC ENANTIOSELECTIVE SYNTHESIS OF FLAVANONES AND CHROMANES | NORTHWESTERN UNIVERSITY (US) | 2009-09-03 | — | — | WO | disclosed |