⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27696050 | 0.97 | — | — | |
| SCHEMBL30240856 | 0.81 | — | — | |
| SCHEMBL6407267 | 0.73 | NPSR1 (0.55) | — | |
| SCHEMBL149636 | 0.72 | — | — | |
| SCHEMBL8098714 | 0.72 | NPC1 (0.35) | — | |
| SCHEMBL31255 | 0.72 | — | — | |
| SCHEMBL10021905 | 0.72 | CCR1 (0.45) | — | |
| SCHEMBL18540406 | 0.69 | KDM4E (0.30) | — | |
| SCHEMBL25185283 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL844387 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512004-B | Synthetic method of 2-fluoro-5-trifluoromethylpyrimidine | 金凯(辽宁)生命科技股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-113512004-A | Synthetic method of 2-fluoro-5-trifluoromethylpyrimidine | 金凯(辽宁)生命科技股份有限公司 | 2021-10-19 | — | — | CN | claimed |
| CN-111995583-A | Synthesis method of 1, 5-dimethylpyrimidine-2 (1H) -ketone | 上海毕得医药科技有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-110372599-A | A kind of synthesis 2,4,6, the method for-three chloro- 5- methylpyrimidines | 南京普锐达医药科技有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110327467-A | The composition that is made of the auxiliary material of hydroxyl and pyrimidines and containing the pharmaceutical preparation of the composition | 黄泳华 | 2019-10-15 | — | — | CN | claimed |
| CN-103435555-B | Preparation method of 4-chloro-5-methylpyrimidine | WYLTON JINGLIN ELECTRONIC MATERIAL CO LTD | 2015-06-24 | — | — | CN | claimed |
| CN-103435555-A | Preparation method of 4-chloro-5-methylpyrimidine | WYLTON JINGLIN ELECTRONIC MATERIAL CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-88101267-A | The method for preparing polychlorophosphnitrile | — | 1988-10-05 | — | — | CN | claimed |
| WO-2026103337-A1 | NOVEL SUBSTITUTED HETEROCYCLIC COMPOUND AS APELIN RECEPTOR MODULATOR | 德睿智药(苏州)新药研发有限公司 | 2026-05-21 | — | — | WO | disclosed |
| CN-118955455-B | Double-target piperine compound used as alpha-glucosidase inhibitor and aldose reductase inhibitor, and preparation method and application thereof | 湘潭大学 | 2026-05-19 | — | — | CN | disclosed |
| US-20260115186-A1 | PIPERIDINE UREA DERIVATIVES FOR CANCER THERAPY | NEUROPN THERAPEUTICS INC. (US) | 2026-04-30 | — | — | US | disclosed |
| EP-4727940-A1 | DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF | Linkcure Therapeutics (KY) | 2026-04-22 | — | — | EP | disclosed |
| US-20260102393-A1 | PIPERIDINE UREA DERIVATIVES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | NEUROPN THERAPEUTICS INC. (US) | 2026-04-16 | — | — | US | disclosed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| CN-88101267-A | The method for preparing polychlorophosphnitrile | — | 1988-10-05 | — | — | CN | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0226837-A2 | Pyri(mi)dyloxy and -thiobenzoic acid derivatives | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |
| EP-0192060-A1 | Heterocyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4248618-A | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof | ICI AUSTRALIA LIMITED (AU) | 1981-02-03 | — | — | US | disclosed |