Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 4/20 | 0.50 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS1 | P29475 | 6/20 | 0.49 |
| ▸ | NOS3 | P29474 | 5/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ARG2 | P78540 | 4/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL422529 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL6034083 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL8678605 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL29050239 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL19816040 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL23608085 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL19816043 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL29050238 | 0.98 | OTC (0.53) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL1790 | 0.98 | OTC (0.56) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL6374054 | 0.98 | OTC (0.56) | OTCDDAH1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116282217-B | Ternary positive electrode material precursor, preparation method thereof, positive electrode material and secondary battery | 广东佳纳能源科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118452369-A | Preparation method of saliva extraction induced liquid of Poecilobdella manillensis | 云南云蛭康生物科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118299531-A | Modified sodium supplementing nano carbon negative electrode material, preparation method thereof and sodium ion battery | 四川启睿克科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-113163811-B | Sparkling beverage with improved taste quality exhibited by sugar and sweetener | 三得利控股株式会社 | 2024-03-26 | — | — | CN | claimed |
| CN-113788865-B | Method for preparing fructose by catalyzing glucose isomerization through ionic liquid loaded by organic metal framework material | 华南理工大学 | 2024-03-19 | — | — | CN | claimed |
| WO-2023119100-A1 | STABLE PHARMACEUTICAL COMPOSITIONS | MANKIND PHARMA LTD. (IN) | 2023-06-29 | — | — | WO | claimed |
| CN-116282217-A | Ternary positive electrode material precursor, preparation method thereof, positive electrode material and secondary battery | 广东佳纳能源科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-20230172824-A1 | Tooth Densensitizing Oral Care Compositions, Devices And Methods | PROCTER & GAMBLE (US) | 2023-06-08 | — | — | US | claimed |
| US-20230055555-A1 | METHOD FOR PREPARING PEPTIDE EMULSION FORMULATION | Sumitomo Pharma Co., Ltd. (JP) | 2023-02-23 | — | — | US | claimed |
| EP-4074332-A1 | METHOD FOR PREPARING PEPTIDE EMULSION FORMULATION | Sumitomo Pharma Co., Ltd. (JP) | 2022-10-19 | — | — | EP | claimed |
| US-20140378490-A1 | Formulations of Phenyl Uracil Compounds | ABBVIE INC. (US) | 2014-12-25 | — | — | US | claimed |
| CN-103768071-A | Oral preparation for treating diabetes | CHINA STATE INST PHARM IND | 2014-05-07 | — | — | CN | claimed |
| EP-2685964-A1 | FORMULATIONS OF PHENYL URACIL COMPOUNDS | AbbVie Inc. (US) | 2014-01-22 | — | — | EP | claimed |
| WO-2012129099-A1 | FORMULATIONS OF PHENYL URACIL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-09-27 | — | — | WO | claimed |
| US-20110117194-A1 | PHARMACEUTICAL FORMULATION CONTAINING ANGIOTENSIN-II RECEPTOR BLOCKER | HANALL BIOPHARMA CO., LTD. (KR) | 2011-05-19 | — | — | US | claimed |
| CN-102065847-A | Pharmaceutical formulation containing angiotensin-II receptor blocker | HANALL PHARMACEUTICAL CO LTD | 2011-05-18 | — | — | CN | claimed |
| EP-2281557-A2 | PHARMACEUTICAL FORMULATION CONTAINING ANGIOTENSIN-II RECEPTOR BLOCKER | HanAll Biopharma Co., Ltd. (KR) | 2011-02-09 | — | — | EP | claimed |
| CN-101450059-A | Anthelmintic agent and preparation method thereof | TIANJIN PACIFIC PHARMACEUTICAL (CN) | 2009-06-10 | — | — | CN | claimed |
| CN-1527701-A | Tablets quickly disintegrated in oral cavity | ������ҩ��ʽ���� | 2004-09-08 | — | — | CN | claimed |
| CN-1091952-A | Cosmetic composition | UNILEVER NV (NL) | 1994-09-14 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055555-A1 | METHOD FOR PREPARING PEPTIDE EMULSION FORMULATION | VIP, IWS1, WFS1 | OTC 2922/4885DDAH1 3166/4885NOS2 4583/4885 |
| US-20140378490-A1 | Formulations of Phenyl Uracil Compounds | UNG, UMPS, TYMP | OTC 266/4885DDAH1 2062/4885NOS2 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.