Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176261 | 0.83 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL3184114 | 0.75 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL3178236 | 0.75 | KCNH2 (0.44) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3162918 | 0.75 | KCNH2 (0.44) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3178384 | 0.75 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL3177668 | 0.74 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL4065072 | 0.74 | SIRT2 (0.39) | — | |
| SCHEMBL3175737 | 0.74 | CYP8B1 (0.40) | KCNH2 | |
| SCHEMBL3176259 | 0.73 | CYP8B1 (0.39) | — | |
| SCHEMBL4070188 | 0.71 | HTR1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773343-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2009-05-13 | — | — | EP | disclosed |
| EP-1773343-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006017326-A1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |