Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231717 | 0.82 | HSP90AA1 (0.57) | HSP90AA1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL2837940 | 0.81 | CXCR2 (0.36) | HSP90AA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL4219785 | 0.76 | GLP1R (0.42) | KDM4EHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL4231314 | 0.76 | MAPK14 (0.36) | KDM4EHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL14000740 | 0.73 | GLP1R (0.33) | MAPK14LMNAL3MBTL1 | |
| SCHEMBL11371403 | 0.73 | HTT (0.36) | PPARGLMNAL3MBTL1MAPK1TDP1 | |
| SCHEMBL4226477 | 0.70 | HSP90AA1 (0.54) | HSP90AA1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL3580582 | 0.69 | IDH1 (0.36) | MEN1KMT2APPARG | |
| SCHEMBL5521888 | 0.69 | GBA1 (0.46) | HSP90AA1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL4225596 | 0.68 | KMT2A (0.35) | MAPTMEN1ALDH1A1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |