Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834616 | 0.81 | GLP1R (0.40) | GLP1RMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL4225977 | 0.76 | HSP90AA1 (0.45) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4231314 | 0.74 | MAPK14 (0.36) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4826868 | 0.74 | GLP1R (0.42) | GLP1RKDM4EALDH1A1LMNA | |
| SCHEMBL4231053 | 0.71 | CXCL8 (0.32) | LMNAKMT2ACNR1MAT2ACNR2 | |
| SCHEMBL13114688 | 0.71 | TRPV1 (0.35) | GLP1RMEN1KMT2AMAPK14 | |
| SCHEMBL27826697 | 0.71 | GLP1R (0.42) | GLP1R | |
| SCHEMBL4232192 | 0.71 | EGLN1 (0.37) | LMNAHPGDTSHR | |
| SCHEMBL4225596 | 0.69 | KMT2A (0.35) | MEN1ALDH1A1MAPTKMT2ACNR1 | |
| SCHEMBL1617276 | 0.68 | MAPK14 (0.73) | MAPK14LIMK1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2092824-A1 | Heterocyclyl pyrimidines | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |