Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051074 | 0.80 | MAPT (0.50) | MAPTCYP1A2MEN1LMNACYP2C9 | |
| SCHEMBL4049872 | 0.80 | MAPT (0.50) | MAPTCYP1A2MEN1LMNACYP2C9 | |
| SCHEMBL4058968 | 0.76 | NAAA (0.52) | CYP1A2LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL4376768 | 0.76 | NAAA (0.52) | CYP1A2LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL4364759 | 0.76 | NAAA (0.52) | CYP1A2LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL4057260 | 0.76 | NAAA (0.52) | CYP1A2LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL512526 | 0.72 | MAPT (0.47) | MAPTCYP1A2MEN1LMNACYP2C9 | |
| SCHEMBL15918524 | 0.72 | CASP1 (0.54) | MAPTCYP1A2MEN1LMNACYP2C9 | |
| SCHEMBL4019614 | 0.71 | MEN1 (0.47) | MAPTMEN1LMNAKMT2AGAA | |
| SCHEMBL4061472 | 0.69 | DHODH (0.44) | MAPTCYP1A2MEN1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |