Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 3/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395342 | 1.00 | IDO1 (0.55) | IDO1ANPEPPDPK1PLAU | |
| SCHEMBL42780 | 1.00 | IDO1 (0.55) | IDO1ANPEPPDPK1PLAU | |
| SCHEMBL6600 | 1.00 | IDO1 (0.55) | IDO1ANPEPPDPK1PLAU | |
| SCHEMBL28840240 | 1.00 | IDO1 (0.55) | IDO1ANPEPPDPK1PLAU | |
| SCHEMBL29858363 | 1.00 | IDO1 (0.55) | IDO1ANPEPPDPK1PLAU | |
| SCHEMBL12787610 | 1.00 | IDO1 (0.55) | IDO1ANPEPPDPK1PLAU | |
| Hydrochloric Acid SCHEMBL1948638 | 0.98 | IDO1 (0.57) | IDO1ANPEPPDPK1 | |
| Hydrochloric Acid SCHEMBL29676818 | 0.98 | IDO1 (0.57) | IDO1ANPEPPDPK1 | |
| Hydrochloric Acid SCHEMBL29397932 | 0.98 | IDO1 (0.57) | IDO1ANPEPPDPK1 | |
| Hydrochloric Acid SCHEMBL2033301 | 0.98 | IDO1 (0.57) | IDO1ANPEPPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1041 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112280761-B | Recombinant transaminase, mutant of recombinant transaminase and application of mutant | 清华大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113030283-A | Rasagiline genotoxic impurity compound and preparation method and application thereof | 上海奥博生物医药技术有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-109180499-B | Preparation method of rasagiline mesylate and intermediate thereof | 上海博志研新药物技术有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-112280761-A | Recombinant transaminase, mutant of recombinant transaminase and application of mutant | 清华大学 | 2021-01-29 | — | — | CN | claimed |
| CN-111333517-A | Improved method for preparing rasagiline | 上海奥博生物医药技术有限公司 | 2020-06-26 | — | — | CN | claimed |
| US-10611775-B2 | Thiophene derivatives | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2020-04-07 | — | — | US | claimed |
| US-20190322684-A1 | THIOPHENE DERIVATIVES | TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) | 2019-10-24 | — | — | US | claimed |
| US-10385062-B2 | Thiophene derivatives | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2019-08-20 | — | — | US | claimed |
| CN-109180499-A | The preparation method of rasagiline mesilate and its intermediate | 上海博志研新药物技术有限公司 | 2019-01-11 | — | — | CN | claimed |
| US-20180099936-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-04-12 | — | — | US | claimed |
| US-7109377-B2 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2006-09-19 | — | — | US | claimed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | claimed |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-01 | — | — | US | claimed |
| US-6448443-B1 | GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-09-10 | — | — | US | claimed |
| US-20020068839-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING 1-AMINOINDAN AND DERIVATIVES THEREOF AND PROCESS FOR PREPARING OPTICALLY ACTIVE 1-AMINOINDAN DERIVATIVES | COHEN SASSON (IL) | 2002-06-06 | — | — | US | claimed |
| US-5994408-A | THERAPY FOR PARKINSON'S DISEASE; ANTICONVULSANT | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1999-11-30 | — | — | US | claimed |
| EP-0738149-A4 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 1999-10-27 | — | — | EP | claimed |
| US-5639913-A | TREATMENT OF PARKINSON'S DISEASE, DEMENTIA, EPILEPSY | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-06-17 | — | — | US | claimed |
| EP-0738149-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385062-B2 | Thiophene derivatives | TSHR, RB1, TAS2R7 | IDO1 2676/4885ANPEP 3462/4885PDPK1 3410/4885 |
| US-10611775-B2 | Thiophene derivatives | TSHR, RB1, TAS2R7 | IDO1 2676/4885ANPEP 3462/4885PDPK1 3410/4885 |
| US-20180099936-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | PDE3A, PDE5A, PDE3B | IDO1 291/4885ANPEP 2538/4885PDPK1 2833/4885 |
| US-20020068839-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING 1-AMINOINDAN AND DERIVATIVES THEREOF AND PROCESS FOR PREPARING OPTICALLY ACTIVE 1-AMINOINDAN DERIVATIVES | PARK7, GAP43, PSEN1 | IDO1 82/4885ANPEP 503/4885PDPK1 1131/4885 |
| US-20190322684-A1 | THIOPHENE DERIVATIVES | TSHR, RB1, TAS2R7 | IDO1 2676/4885ANPEP 3462/4885PDPK1 3410/4885 |
| US-20030082830-A1 | Synthesis of combinatorial libraries of compounds reminiscent of natural products | TKFC, NISCH, PTGIS | IDO1 47/4885ANPEP 1026/4885PDPK1 2005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.