Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383746 | 0.95 | HDAC1 (0.47) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4224435 | 0.91 | HDAC1 (0.47) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4229534 | 0.89 | HDAC3 (0.46) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL3230138 | 0.89 | UTS2R (0.47) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4234564 | 0.88 | UTS2R (0.40) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4224033 | 0.87 | HDAC1 (0.51) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4225149 | 0.87 | HDAC1 (0.50) | HDAC1HDAC3HDAC8HDAC2UTS2R | |
| SCHEMBL4368308 | 0.86 | HDAC1 (0.47) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4223952 | 0.86 | HDAC1 (0.46) | HDAC1HDAC3HDAC8HDAC2NCOR2 | |
| SCHEMBL4219358 | 0.86 | HDAC3 (0.46) | HDAC1HDAC3HDAC8HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |