Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL4963616 | 0.96 | WDR5 (0.59) | WDR5LDHAHSD17B10MEN1KMT2A | |
| Paraben SCHEMBL5972646 | 0.94 | LDHA (0.56) | WDR5LDHAHSD17B10MEN1KMT2A | |
| Terephthalic Acid SCHEMBL7190729 | 0.94 | WDR5 (0.53) | WDR5LDHAHSD17B10MEN1KMT2A | |
| SCHEMBL27804512 | 0.93 | WDR5 (0.68) | WDR5LDHAHSD17B10MEN1KMT2A | |
| SCHEMBL33850 | 0.93 | WDR5 (0.68) | WDR5LDHAHSD17B10MEN1KMT2A | |
| Benzene SCHEMBL27549874 | 0.93 | WDR5 (0.68) | WDR5LDHAHSD17B10MEN1KMT2A | |
| SCHEMBL29376013 | 0.93 | WDR5 (0.68) | WDR5LDHAHSD17B10MEN1KMT2A | |
| SCHEMBL7024975 | 0.92 | WDR5 (0.54) | WDR5LDHAHSD17B10MEN1KMT2A | |
| SCHEMBL11239275 | 0.91 | WDR5 (0.58) | WDR5LDHAHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL608188 | 0.91 | LDHA (0.69) | WDR5LDHAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109648976-A | A kind of co-extruding biaxial stretched PET/PPS laminated film and preparation method thereof | 四川东方绝缘材料股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| US-20120022194-A1 | PARTIALLY AROMATIC POLYAMIDE MOULDING COMPOSITIONS AND THEIR USES | EMS-PATENT AG (CH) | 2012-01-26 | — | — | US | claimed |
| CN-110140086-A | Printable composition comprising polymer and polymerizable component, article and method of making article therefrom | 3M创新有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-109648976-A | A kind of co-extruding biaxial stretched PET/PPS laminated film and preparation method thereof | 四川东方绝缘材料股份有限公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-105246942-B | Copolyesterimides derived from N, N' -bis (hydroxyalkyl) -pyromellitic diimide and films made therefrom | 杜邦帝人薄膜美国有限公司 | 2017-06-20 | — | — | CN | disclosed |
| CN-103946285-B | Polyester film, solar cell backboard, solar cell | 东丽株式会社 | 2016-07-06 | — | — | CN | disclosed |
| CN-101535371-B | Polyether ester elastomer composition | DU PONT | 2012-08-29 | — | — | CN | disclosed |
| US-7982952-B2 | Polarization component, polarization light source and image display apparatus using the same | NITTO DENKO CORPORATION (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20100226007-A1 | POLARIZATION COMPONENT, POLARIZATION LIGHT SOURCE AND IMAGE DISPLAY APPARATUS USING THE SAME | NITTO DENKO CORPORATION (JP) | 2010-09-09 | — | — | US | disclosed |
| US-7746555-B2 | Polarizer, polarization light source and image display unit using them | NITTO DENKO CORPORATION (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090034070-A1 | POLARIZER, POLARIZATION LIGHT SOURCE AND IMAGE DISPLAY UNIT USING THEM | NITTO DENKO CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| US-5932685-A | HAVING SPECIFIED RATIO OF SHRINKABILITY IN HOT WATER AT FIVE SECONDS TO THAT AT 30 SECONDS; VERY LITTLE SHRINKAGE SPOTS AND STRAINS AFTER SHRINKAGE; LABELS | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0602446-B1 | Method for forming a color image | FUJI PHOTO FILM CO LTD (JP) | 1999-02-03 | — | — | EP | disclosed |
| EP-0826482-A2 | Heat-shrinkable polyester films | Toyo Boseki Kabushiki Kaisha (JP) | 1998-03-04 | — | — | EP | disclosed |
| US-5556737-A | LIGHT SENSITIVE ELEMENTS WITH CYAN, MAGENTA AND YELLOW COLOR FORMING EMULSION LAYERS WITH WHITE PIGMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5474884-A | A non-photosensitive hydrophilic colloid multilayer comprising a layer of white pigment dispersing in a waterproofing polyester, a layer containing at least one color-mix inhibitor having a molecular weight of 350 or more | FUJI PHOTO FILM CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| CN-1112573-A | Thermoplastic polyesters possessing high stability in the molten state | ENICHEM SPA (IT) | 1995-11-29 | — | — | CN | disclosed |
| US-5462845-A | Having reflective support surface coated with white pigment dispersed in polyester, containing specifed yellow dye-forming coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| US-5437970-A | Reflective support having a polyester/white pigment coating and a nonphotosensitive hydrophilic colloid layer containing a dispersion of solid fine particles of a ionizable chromophore; image sharpness; antisoilants; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| CN-1101652-A | Compatible thermoplastic compositions based on polyesters and polycarbonates | ENICHEM SPA (IT) | 1995-04-19 | — | — | CN | disclosed |