Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA known ✓ | P06280 | 2/20 | 0.59 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.69 |
| ▸ | WDR5 | P61964 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2383857 | 1.00 | LDHA (0.69) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| SCHEMBL33850 | 0.98 | WDR5 (0.68) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| Benzene SCHEMBL27549874 | 0.98 | WDR5 (0.68) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| SCHEMBL27804512 | 0.98 | WDR5 (0.68) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| SCHEMBL29376013 | 0.98 | WDR5 (0.68) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| Naphthalene SCHEMBL1831655 | 0.96 | WDR5 (0.66) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| Ammonia Solution, Strong SCHEMBL8803959 | 0.96 | WDR5 (0.66) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| SCHEMBL964273 | 0.96 | WDR5 (0.66) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| SCHEMBL18812861 | 0.96 | WDR5 (0.66) | LDHAWDR5ALDH1A1HPGDKDM4E | |
| SCHEMBL4577224 | 0.96 | WDR5 (0.66) | LDHAWDR5ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260054227-A1 | COMPOSITE MEMBRANE AND METHOD OF MAKING THE SAME | H2MO TECH PTE LTD (SG) | 2026-02-26 | — | — | US | claimed |
| US-12485388-B2 | Composite membrane and method of making the same | H2MO TECHNOLOGY PTE LTD (SG) | 2025-12-02 | — | — | US | claimed |
| CN-119565382-A | Method for cleaning reverse osmosis membrane and reverse osmosis membrane prepared by same | 万华化学集团股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-115845615-B | High-flux polyethylene-based reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-113766966-B | Composite film and method for producing same | 南洋理工大学 | 2024-08-27 | — | — | CN | claimed |
| CN-114146567-B | Preparation process of epoxy modified reverse osmosis membrane, reverse osmosis membrane and application of reverse osmosis membrane | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-114146566-B | Preparation method of high-performance polyolefin substrate reverse osmosis membrane, reverse osmosis membrane and application | 万华化学集团股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-115583834-B | High-performance aramid-based graphite film and preparation method thereof | 浙江中科玖源新材料有限公司 | 2024-02-20 | — | — | CN | claimed |
| US-20230330604-A1 | MOLECULARLY POROUS CROSS-LINKED MEMBRANES | UNIV KING ABDULLAH SCI & TECH (SA) | 2023-10-19 | — | — | US | claimed |
| CN-112827368-B | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-112827368-A | Anti-pollution reverse osmosis membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-111715083-A | Modified polyamide desalting layer, reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-09-29 | — | — | CN | claimed |
| CN-111632498-A | Preparation method of non-woven fabric substrate supported polyethylene nanofiltration membrane | 上海恩捷新材料科技有限公司 | 2020-09-08 | — | — | CN | claimed |
| US-10730819-B2 | Naphthalenedicarboxylic acid dichloride production method | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-08-04 | — | — | US | claimed |
| CN-111039779-A | Process for producing naphthalenedicarboxylic dichloride | 京瓷办公信息系统株式会社 | 2020-04-21 | — | — | CN | claimed |
| US-20200115313-A1 | NAPHTHALENEDICARBOXYLIC ACID DICHLORIDE PRODUCTION METHOD | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-16 | — | — | US | claimed |
| US-20160263530-A1 | FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) | 2016-09-15 | — | — | US | claimed |
| EP-1020218-B1 | COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME | NITTO DENKO CORP (JP) | 2003-05-21 | — | — | EP | claimed |
| EP-1020218-A1 | COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME | NITTO DENKO CORPORATION (JP) | 2000-07-19 | — | — | EP | claimed |
| US-4617368-A | DICARBOXYLIC ACID DICHLORIDE USED AS STARTING MATERIALS PREPARED BY CHLORINATION OF DIMETHYL ESTERS; TERTIARY AMINES AS CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115313-A1 | NAPHTHALENEDICARBOXYLIC ACID DICHLORIDE PRODUCTION METHOD | DDT, DHODH, DLD | GLA 1575/4885GAA 2062/4885LDHA 383/4885 |
| US-20260054227-A1 | COMPOSITE MEMBRANE AND METHOD OF MAKING THE SAME | AQP1, AQP4, AQP3 | GLA 3275/4885GAA 4174/4885LDHA 3142/4885 |
| US-10730819-B2 | Naphthalenedicarboxylic acid dichloride production method | DDT, DHODH, DLD | GLA 1575/4885GAA 2062/4885LDHA 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.