Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219712 | 0.90 | UTS2R (0.39) | ALDH1A1GAASMN1; SMN2RAB9APKM | |
| SCHEMBL3218525 | 0.89 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2RAB9APKMNPC1 | |
| SCHEMBL4225149 | 0.88 | HDAC1 (0.50) | ALDH1A1GAASMN1; SMN2RAB9APKM | |
| SCHEMBL4234564 | 0.87 | UTS2R (0.40) | ALDH1A1SMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL4234963 | 0.85 | KIT (0.40) | RAB9AMAPTMEN1KMT2AHDAC1 | |
| SCHEMBL3234241 | 0.85 | RAB9A (0.42) | ALDH1A1SMN1; SMN2RAB9APKMNPC1 | |
| SCHEMBL3229690 | 0.84 | RAB9A (0.40) | ALDH1A1SMN1; SMN2RAB9APKMNPC1 | |
| SCHEMBL3223205 | 0.83 | TMEM97 (0.39) | HDAC1UTS2R | |
| SCHEMBL3230263 | 0.82 | MCHR1 (0.41) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL3234623 | 0.82 | TMEM97 (0.39) | HDAC1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |