Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028207 | 0.78 | S1PR3 (0.47) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL4138519 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HSD17B10KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7461862 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL12915380 | 0.77 | S1PR3 (0.49) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL10020390 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL7469957 | 0.74 | S1PR3 (0.47) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL11732619 | 0.74 | S1PR3 (0.47) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL9094486 | 0.74 | S1PR3 (0.47) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL28818196 | 0.74 | S1PR3 (0.47) | ALDH1A1HSD17B10S1PR3KDM4ELMNA | |
| SCHEMBL4289764 | 0.74 | MGAM (0.49) | ALDH1A1HSD17B10S1PR3KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024095-A1 | METHOD OF MAKING AND ADMINISTERING QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-02-26 | — | — | WO | disclosed |