Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818196 | 0.85 | S1PR3 (0.47) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL12915380 | 0.80 | S1PR3 (0.49) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL1129147 | 0.79 | NCF1 (0.46) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL2028207 | 0.77 | S1PR3 (0.47) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL11732619 | 0.77 | S1PR3 (0.47) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL7469957 | 0.77 | S1PR3 (0.47) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL18426840 | 0.76 | CYP1A2 (0.48) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL9009627 | 0.74 | NCF1 (0.50) | S1PR3NCF1NOS2BACE1CA12 | |
| Bromide SCHEMBL1866312 | 0.74 | CYP1A2 (0.47) | S1PR3NCF1NOS2BACE1CA12 | |
| SCHEMBL7995244 | 0.74 | ALDH1A1 (0.51) | S1PR3NCF1NOS2BACE1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541196-A | ANTIPROTOZOA AGENTS | INSTITUT FRANCAIS DE RECHERCHE SCIENTIFIQUE POUR LE DEVELOPPMENT EN COOPERATION (ORSTOM) (FR) | 1996-07-30 | — | — | US | disclosed |