Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27967550 | 0.82 | TDP1 (0.35) | PDPK1CYP2A6METAP1RAB9AKDM4C | |
| SCHEMBL5076868 | 0.77 | PDPK1 (0.36) | PDPK1CYP2A6METAP1RAB9AADRA1D | |
| SCHEMBL5902312 | 0.74 | RAB9A (0.48) | PDPK1CYP2A6METAP1RAB9AADRA1D | |
| SCHEMBL102331 | 0.69 | PDPK1 (0.59) | PDPK1CYP2A6METAP1RAB9ALOXL2 | |
| SCHEMBL1288402 | 0.69 | POLB (0.50) | PDPK1CYP2A6METAP1RAB9ALOXL2 | |
| SCHEMBL24697624 | 0.68 | KDM4C (0.33) | KDM4CCDK5CDK5R1KDRBCHE | |
| SCHEMBL19368365 | 0.68 | ADRA2A (0.44) | PDPK1CYP2A6LOXL2HSP90AA1 | |
| SCHEMBL30534095 | 0.67 | PDPK1 (0.56) | PDPK1CYP2A6METAP1RAB9ALOXL2 | |
| SCHEMBL31556353 | 0.67 | PDPK1 (0.56) | PDPK1CYP2A6METAP1RAB9ALOXL2 | |
| SCHEMBL30632310 | 0.67 | PDPK1 (0.56) | PDPK1CYP2A6METAP1RAB9ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003132-A | A kind of thiazoles IDO inhibitor and preparation method thereof | 河南师范大学 | 2019-07-12 | — | — | CN | claimed |
| CN-102532050-A | Preparation method for 2-amido substitutional oxazole (thioazole) derivative | LANZHOU CHEM PHYS INST | 2012-07-04 | — | — | CN | claimed |
| EP-1819721-A1 | MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE | Plant Bioscience Limited (GB) | 2007-08-22 | — | — | EP | claimed |
| US-20060128673-A1 | Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions | ABBOTT PRODUCTS GMBH (DE) | 2006-06-15 | — | — | US | claimed |
| WO-2006054102-A1 | MICROCIN B17 ANALOGS AND METHODS FOR THEIR PREPARATION AND USE | PLANT BIOSCIENCE LIMITED (GB) | 2006-05-26 | — | — | WO | claimed |
| EP-0583806-B1 | Acrylic derivatives of 2-thiazolypyrroles having a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-10-15 | — | — | EP | claimed |
| EP-0554956-B1 | Thiazolylpyrroles having a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1997-10-01 | — | — | EP | claimed |
| US-5334605-A | Agricultural uses | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E (IT) | 1994-08-02 | — | — | US | claimed |
| EP-0583806-A1 | Acrylic derivatives of 2-thiazolypyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-02-23 | — | — | EP | claimed |
| EP-0554956-A1 | Thiazolylpyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | claimed |
| JP-6293757-A | — | — | None | — | — | JP | disclosed |
| CN-115867442-A | Composition for elastomeric compounds comprising a tetrazole compatibiliser and tyre comprising such a composition | 倍耐力轮胎股份公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11193065-B2 | Liquid crystal composition, method of producing the same, and retardation film constituted from the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-12-07 | — | — | US | disclosed |
| EP-3831940-A1 | SMALL MOLECULE INHIBITORS OF CRISPR-CAS ASSOCIATED ACTIVITY | Danmarks Tekniske Universitet (DK) | 2021-06-09 | — | — | EP | disclosed |
| EP-3831940-A1 | SMALL MOLECULE INHIBITORS OF CRISPR-CAS ASSOCIATED ACTIVITY | Danmarks Tekniske Universitet (DK) | 2021-06-09 | — | — | EP | disclosed |
| EP-0583806-A1 | Acrylic derivatives of 2-thiazolypyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-02-23 | — | — | EP | disclosed |
| EP-0583806-A1 | Acrylic derivatives of 2-thiazolypyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1994-02-23 | — | — | EP | disclosed |
| EP-0554956-A1 | Thiazolylpyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |
| EP-0554956-A1 | Thiazolylpyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |
| EP-0554956-A1 | Thiazolylpyrroles having a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128673-A1 | Pharmaceutical compositions comprising CB1 cannabinoid receptor antagonists and potassium channel openers for the treatment of obesity and related conditions | CNR1, CNR2, KCNJ11 | PDPK1 657/4885CYP2A6 802/4885METAP1 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.