Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422977 | 0.77 | PDPK1 (0.48) | PDPK1CDK5CDK5R1CYP2A6ADORA2A | |
| SCHEMBL6798332 | 0.73 | PDPK1 (0.33) | PDPK1CYP2A6ADORA2AADORA1METAP1 | |
| SCHEMBL4211068 | 0.69 | ALDH1A1 (0.37) | PDPK1CDK5CDK5R1ADORA2AADORA1 | |
| SCHEMBL10917272 | 0.66 | ADORA1 (0.45) | PDPK1CYP2A6ADORA2AADORA1METAP1 | |
| SCHEMBL7108445 | 0.66 | SMPD3 (0.40) | PDPK1CYP2A6ADORA1RAB9A | |
| SCHEMBL30977584 | 0.65 | PDPK1 (0.42) | PDPK1CYP2A6ADORA2AADORA1METAP1 | |
| SCHEMBL8066803 | 0.64 | ADORA2A (0.33) | ADORA2AADORA1 | |
| Tert-Butyl Formate SCHEMBL27967550 | 0.63 | TDP1 (0.35) | PDPK1CYP2A6ADORA2AADORA1METAP1 | |
| SCHEMBL5902312 | 0.62 | RAB9A (0.48) | PDPK1CYP2A6ADORA2AADORA1METAP1 | |
| SCHEMBL4078462 | 0.62 | PDPK1 (0.43) | PDPK1CYP2A6ADORA2AADORA1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385379-B1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2008-08-06 | — | — | EP | disclosed |
| US-7217831-B2 | Insecticide and method of controlling insects | NUFARM - AUSTRALIA LIMITED (AU) | 2007-05-15 | — | — | US | disclosed |
| US-20040176424-A1 | Insecticide and method of controlling insects | NUFARM AUSTRALIA LIMITED (AU) | 2004-09-09 | — | — | US | disclosed |
| EP-1385379-A4 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LTD (AU) | 2004-06-23 | — | — | EP | disclosed |
| EP-1385379-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002078448-A1 | INSECTICIDE AND METHOD OF CONTROLLING INSECTS | NUFARM AUSTRALIA LIMITED (AU) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176424-A1 | Insecticide and method of controlling insects | DDT, CYP2B6, NR4A1 | PDPK1 4030/4885CDK5 3792/4885CDK5R1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.