SCHEMBL4230907

SCHEMBL4230907

CC(C)[SiH2]C(C)C.C[SiH2]c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 1/20 0.32
TRPA1 O75762 2/20 0.31
TAAR1 Q96RJ0 4/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP2A6 P11509 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 2/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2C P18825 1/20 0.30
CYP2D6 P10635 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67968 0.86
Hydrochloric Acid SCHEMBL5702841 0.83 TSHR (0.37) TDP1TSHRLMNAALOX12ACHE
Ammonia Solution, Strong SCHEMBL28586237 0.83
Hydrochloric Acid SCHEMBL7937814 0.83 TSHR (0.37) TDP1TSHRLMNAALOX12ACHE
Fluoride SCHEMBL29655462 0.83
SCHEMBL9718210 0.83 TSHR (0.37) TDP1TSHRLMNAALOX12ACHE
Hydrochloric Acid SCHEMBL5165959 0.80 TSHR (0.35) TDP1TSHRLMNAALOX12ACHE
SCHEMBL28535293 0.80 TSHR (0.36) TRPA1TSHRLMNAALOX12ACHE
Trimethylammonium SCHEMBL11075798 0.78 TSHR (0.36) TDP1TAAR1SIGMAR1TSHRLMNA
SCHEMBL7785325 0.78 TSHR (0.35) TSHRLMNAALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090326097-A1 SURFACE-COATED ALUMINUM OXIDE NANOPARTICLE AND RESIN COMPOSITION THEREOF NISSAN MOTOR CO., LTD. 2009-12-31 US disclosed
EP-2048189-A1 SURFACE-COATED ALUMINUM OXIDE NANOPARTICLE AND RESIN COMPOSITION THEREOF Nissan Motor Co., Ltd. (JP) 2009-04-15 EP disclosed