Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033599 | 0.81 | ACACA (0.56) | KDM4ENPC1ALDH1A1RAB9ACYP1A2 | |
| SCHEMBL16810259 | 0.80 | ACACA (0.55) | KDM4EALDH1A1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL13241182 | 0.79 | CYP1A2 (0.49) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4236363 | 0.78 | MAPT (0.63) | KDM4ENPC1ALDH1A1RAB9AHPGD | |
| SCHEMBL16293710 | 0.76 | KDM4E (0.50) | KDM4ENPC1ALDH1A1RAB9ACYP1A2 | |
| SCHEMBL23951 | 0.75 | MAPT (0.59) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL1791444 | 0.74 | CYP1A2 (0.53) | NPC1ALDH1A1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL13241180 | 0.74 | MAOB (0.49) | NPC1ALDH1A1RAB9ACYP1A2CYP3A4 | |
| Hydrogen Sulfide SCHEMBL29093271 | 0.73 | MAPT (0.58) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL28878462 | 0.73 | RAB9A (0.60) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098520-B1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | ESSILOR INT (FR) | 2013-07-03 | — | — | EP | disclosed |
| EP-2098520-B1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | ESSILOR INT (FR) | 2013-07-03 | — | — | EP | disclosed |
| EP-2098520-A1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-09-09 | — | — | EP | disclosed |
| EP-2098520-A1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-09-09 | — | — | EP | disclosed |