SCHEMBL423161

SCHEMBL423161

C=C(C)C(=O)OCCCCOP(=O)([O-])OCC[N+](C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
AKT1 P31749 2/20 0.57
ESR1 P03372 1/20 0.57
ADORA3 P0DMS8 1/20 0.57
CDC25A P30304 1/20 0.57
AGTR1 P30556 1/20 0.57
ADRA1A P35348 1/20 0.57
KCNH2 Q12809 1/20 0.57
TSHR P16473 2/20 0.47
ADRA1D P25100 1/20 0.47
PTAFR P25105 1/20 0.47
HTR1D P28221 1/20 0.47
HTR2C P28335 1/20 0.47
ADRA1B P35368 1/20 0.47
DRD3 P35462 1/20 0.47
TMEM97 Q5BJF2 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 1/20 0.44
PRKD3 O94806 1/20 0.43
PRKCG P05129 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120096 0.99 LMNA (0.60) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL223046 0.99 LMNA (0.60) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL2118062 0.99 LMNA (0.60) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260875 0.99 LMNA (0.60) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL2117527 0.99 LMNA (0.60) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL2122717 0.99 LMNA (0.60) LMNAAKT1ESR1ADORA3CDC25A
Phosphoric Acid SCHEMBL2035967 0.97 LMNA (0.55) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1261204 0.97 LMNA (0.54) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1260055 0.94 AKT1 (0.50) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1261300 0.94 AKT1 (0.50) LMNAAKT1ESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4369081-A2 METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT Alcon Inc. (CH) 2024-05-15 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
US-11931454-B2 Wet-packed soft hydrogel ocular inserts ALCON INC. (CH) 2024-03-19 US claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-11867874-B2 Insert materials with high oxygen permeability and high refractive index ALCON INC. (CH) 2024-01-09 US claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 US claimed
US-20130306550-A1 REVERSE OSMOSIS MEMBRANE HAVING GOOD ANTIFOULING PROPERTIES AND METHOD OF MANUFACTURING THE SAME LG CHEM, LTD. (KR) 2013-11-21 US claimed
EP-2662070-A2 CROSS-LINKED COPOLYMER CONTAINING PHOSPHORYLCHOLINE MONOMER AND COSMETIC COMPOSITION CONTAINING SAME KCI Limited. (KR) 2013-11-13 EP claimed
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same KCI LIMITED (KR) 2013-11-07 US claimed
US-8278097-B2 Method for forming embryoid bodies NOF CORPORATION (JP) 2012-10-02 US claimed
US-20090246871-A1 For forming embryoid bodies from embryonic stem (ES) cells easily and efficiently without complicated technique NOF CORPORATION (JP) 2009-10-01 US claimed
US-20060252148-A1 For forming embryoid bodies from embryonic stem (ES) cells easily and efficiently without complicated technique NOF CORPORATION (JP) 2006-11-09 US claimed
WO-2003026489-A2 BIOPOLYMER AND BIOPOLYMER-CELL COMPOSITIONS FOR NERVE TISSUE REPAIR UNIVERSITY OF FLORIDA (US) 2003-04-03 WO claimed
EP-0537972-B1 Treating solution for contact lenses NOF CORP (JP) 1996-07-10 EP claimed
US-5461433-A Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups NOF CORPORATION (JP) 1995-10-24 US claimed
EP-0537972-A1 Treating solution for contact lenses NOF CORPORATION (JP) 1993-04-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130295038-A1 Cross-Linked Copolymer Containing Phosphorylcholine Monomer and Cosmetic Composition Containing Same PHOSPHO1, SGMS1, SGMS2 LMNA 1174/4885AKT1 244/4885ESR1 1448/4885
US-11931454-B2 Wet-packed soft hydrogel ocular inserts BRI3BP, BRWD1, HRH2 LMNA 3870/4885AKT1 3897/4885ESR1 2459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.