Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163153 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL9489186 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL3275768 | 0.79 | DPP4 (0.46) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL6996541 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL423788 | 0.79 | AOC3 (0.49) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL4493633 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL232141 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL9349254 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPK1SRD5A2AOC3TXNRD1 | |
| SCHEMBL10749290 | 0.73 | TXNRD1 (0.62) | ALDH1A1MAPK1SRD5A2TXNRD1TXNRD3 | |
| SCHEMBL10431721 | 0.72 | FOLH1 (0.49) | ALDH1A1MAPK1SRD5A2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | CCNT1, XPO4, XDH | ALDH1A1 3095/4885MAPK1 730/4885SRD5A2 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.