Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164465 | 0.86 | RAB9A (0.58) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL1854415 | 0.86 | HSD17B10 (0.48) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL7116087 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL379230 | 0.77 | PRKCI (0.56) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL29364809 | 0.77 | PRKCI (0.56) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL11096599 | 0.77 | NPC1 (0.58) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL17819964 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL2382432 | 0.77 | LMNA (0.69) | SMN1; SMN2LMNANPC1RAB9AMAPKAPK2 | |
| SCHEMBL1122456 | 0.74 | MAPT (0.40) | SMN1; SMN2LMNANPC1RAB9ACASP1 | |
| SCHEMBL266080 | 0.74 | PRKCI (0.49) | SMN1; SMN2LMNANPC1RAB9ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | SMN1; SMN2 1538/4885LMNA 2227/4885NPC1 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.