SCHEMBL423301

SCHEMBL423301

O=S(=O)(O)c1cc(O)c2c(O)cccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 2/20 0.56
DUSP5 Q16690 1/20 0.53
ALDH1A1 P00352 6/20 0.51
HSD17B10 Q99714 4/20 0.51
CYP2C9 P11712 3/20 0.51
CYP2C19 P33261 2/20 0.51
HIF1A Q16665 1/20 0.51
TSHR P16473 2/20 0.50
APEX1 P27695 1/20 0.49
PTPN1 P18031 2/20 0.48
MEN1 O00255 1/20 0.48
DNMT1 P26358 1/20 0.48
CACNA1B Q00975 1/20 0.48
APBA1 Q02410 1/20 0.48
KMT2A Q03164 1/20 0.48
MCL1 Q07820 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
NSD2 O96028 3/20 0.47
CASP6 P55212 3/20 0.47
DUSP3 P51452 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5637719 0.98 NT5E (0.54) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL10905229 0.98 NT5E (0.54) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL2875633 0.86 ALDH1A1 (0.55) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL465011 0.86 DUSP5 (0.62) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL18274854 0.86 DUSP5 (0.62) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL30491182 0.86 DUSP5 (0.62) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL10878651 0.85 DUSP5 (0.53) NT5EDUSP5ALDH1A1HSD17B10TSHR
SCHEMBL11307786 0.84 DUSP5 (0.60) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
SCHEMBL3928588 0.84 NT5E (0.70) NT5EDUSP5ALDH1A1HSD17B10CYP2C9
Potassium SCHEMBL18274869 0.84 DUSP5 (0.60) NT5EDUSP5ALDH1A1HSD17B10CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102256610-A Probiotic formulations BRACCO IMAGING SPA 2011-11-23 CN claimed
US-20110206650-A1 Probiotic Formulations BRACCO IMAGING S.P.A. (IT) 2011-08-25 US claimed
US-7935331-B2 Applying a polymer of vanillin monomers, o-vanillin monomers; peptides, polyethers, polyesters JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2011-05-03 US claimed
EP-2206506-A1 Probiotic formulations Bracco Imaging S.p.A (IT) 2010-07-14 EP claimed
EP-1701689-B1 VANILLIN POLYMERS FOR USE IN DARKENING THE SKIN JOHNSON & JOHNSON CONSUMER (US) 2010-02-10 EP claimed
EP-2045297-A2 Compositions for use in darkening skin Johnson and Johnson Consumer Companies, Inc. (US) 2009-04-08 EP claimed
US-20090087395-A1 COMPOSITIONS FOR USE IN DARKENING THE SKIN JOHNSON & JOHNSON CONSUMER CO., INC. 2009-04-02 US claimed
US-7081442-B2 Composition containing a peptide and a pigment and the use thereof in darkening the skin JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2006-07-25 US claimed
US-7025951-B2 Compositions and methods for darkening the skin JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2006-04-11 US claimed
US-20050129633-A1 Vanillin polymers for use in darkening the skin KENVUE BRANDS LLC 2005-06-16 US claimed
EP-0820275-A4 COSMETIC MELANINS UNIV YALE (US) 2000-03-08 EP claimed
US-5744125-A OXIDATIVE POLYMERIZATION OF PRECURSORS THAT ENHANCE SUBSTANTIVITY OR ADHERENCE TO HAIR OR SKIN YALE UNIVERSITY (US) 1998-04-28 US claimed
EP-0820275-A1 COSMETIC MELANINS YALE UNIVERSITY (US) 1998-01-28 EP claimed
WO-1996025920-A9 COSMETIC MELANINS 1996-10-31 WO claimed
WO-1996025920-A1 COSMETIC MELANINS YALE UNIVERSITY (US) 1996-08-29 WO claimed
US-20250333472-A1 Binding Domain Mapping and Compounds, Compositions, Complexes, Methods, and Kits Related Thereto GEORGE MASON RES FOUNDATION INC (US) 2025-10-30 US disclosed
US-12331096-B2 Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto George Mason Research Foundation, Inc. (US) 2025-06-17 US disclosed
US-3950171-A THERMOPLASTIC RESIN DIAZONIUM SALT MITA INDUSTRIAL CO. LTD. (JA) 1976-04-13 US disclosed
US-3948661-A Process for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LTD. (JA) 1976-04-06 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050129633-A1 Vanillin polymers for use in darkening the skin VCL, CUTA, DPM1 NT5E 2733/4885DUSP5 2678/4885ALDH1A1 383/4885
US-20250333472-A1 Binding Domain Mapping and Compounds, Compositions, Complexes, Methods, and Kits Related Thereto SNRPE, SSBP1, RPA1 NT5E 2959/4885DUSP5 3041/4885ALDH1A1 4743/4885
US-20090087395-A1 COMPOSITIONS FOR USE IN DARKENING THE SKIN TYR, CUTA, MC1R NT5E 657/4885DUSP5 3282/4885ALDH1A1 371/4885
US-12331096-B2 Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto SNRPE, SSBP1, RPA1 NT5E 2959/4885DUSP5 3041/4885ALDH1A1 4743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.