Sugi Predict

Sugi Predict / Compounds / SCHEMBL2875633

SCHEMBL2875633

SCHEMBL2875633

O=S(=O)(O)c1cc(S(=O)(=O)O)c2c(O)cccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.55
▸ MAPK1 P28482 2/20 0.55
▸ DUSP5 Q16690 1/20 0.50
▸ TSHR P16473 2/20 0.48
▸ MEN1 O00255 1/20 0.46
▸ DNMT1 P26358 1/20 0.46
▸ CACNA1B Q00975 1/20 0.46
▸ APBA1 Q02410 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ MCL1 Q07820 1/20 0.46
▸ APOBEC3G Q9HC16 1/20 0.46
▸ CYP2C9 P11712 4/20 0.45
▸ CYP1A2 P05177 3/20 0.45
▸ DNASE1L3 Q13609 1/20 0.45
▸ NT5E P21589 2/20 0.45
▸ AURKA O14965 1/20 0.45
▸ AURKB Q96GD4 1/20 0.45
▸ SUMO2 P61956 1/20 0.45
▸ SUMO1 P63165 1/20 0.45
▸ SENP7 Q9BQF6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1806912 0.90 DUSP5 (0.48) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL465011 0.86 DUSP5 (0.62) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL30491182 0.86 DUSP5 (0.62) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL18274854 0.86 DUSP5 (0.62) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL5171487 0.86 ALDH1A1 (0.51) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL423301 0.86 NT5E (0.56) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL18274852 0.85 DUSP5 (0.60) ALDH1A1MAPK1DUSP5TSHRMEN1
Potassium SCHEMBL18274869 0.85 DUSP5 (0.60) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL18274867 0.85 DUSP5 (0.60) ALDH1A1MAPK1DUSP5TSHRMEN1
SCHEMBL10905229 0.84 NT5E (0.54) ALDH1A1MAPK1DUSP5TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020142700-A1 BINDING DOMAIN MAPPING AND COMPOUNDS, COMPOSITIONS, COMPLEXES, METHODS, AND KITS RELATED THERETO George Mason Research Foundation, Inc. (US) 2020-07-09 — — WO disclosed
CN-102566269-B Coloured composition, colour filter and display element JSR株式会社 2016-06-15 — — CN disclosed
EP-2252375-A1 MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL Sederma (FR) 2010-11-24 — — EP disclosed
US-20090324656-A1 COSMETIC PREPARATIONS WITH AN ADDITIVE FROM THE BAOBAB TREE ENGELS PETER 2009-12-31 — — US disclosed
WO-2009104118-A1 MOISTURIZING COSMETIC COMPOSITION COMPRISING A COMBINATION OF HOMARINE AND ERYTHRITOL SEDERMA (FR) 2009-08-27 — — WO disclosed
EP-1824470-A4 METHOD FOR EXTENDING LIFESPAN AND DELAYING THE ONSET OF AGE-RELATED DISEASE CASH ALAN BRIAN (US) 2009-07-01 — — EP disclosed
EP-1824470-A2 METHOD FOR EXTENDING LIFESPAN AND DELAYING THE ONSET OF AGE-RELATED DISEASE Cash, Alan Brian (US) 2007-08-29 — — EP disclosed
WO-2006066244-A2 METHOD FOR EXTENDING LIFESPAN AND DELAYING THE ONSET OF AGE-RELATED DISEASE CASH ALAN B (US) 2006-06-22 — — WO disclosed
US-20050238679-A1 Taurine-containing preparations for improving the skin barrier BEIERSDORF AG (DE) 2005-10-27 — — US disclosed
WO-2003070161-A2 EMULSIFIED SKIN CARE COMPOSITION CONTAINING SALICYLIC ACID, LANOLIN OIL, AND PROPYLENE GLYCOL ALWYN COMPANY, INC. (US) 2003-08-28 — — WO disclosed
US-5116956-A POLYAZO DYE COMPOUNDS HAVING VINYLSULFONE TYPE AND PYRIDINIUM TYPE FIBER REACTIVE GROUPS SUMITOMO CHEMICAL CO., LTD. (JP) 1992-05-26 — — US disclosed
US-5112959-A Dyes for cellulose, polyamides and polyurethanes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-05-12 — — US disclosed
EP-0481449-A2 Ink compositions for ink jet recording SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-22 — — EP disclosed
US-5104978-A Colorfast chemical resistant dyes for cellulose fibers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-14 — — US disclosed
EP-0400647-A1 Polyazo dye compounds having vinylsulfone type and pyridinium type fiber reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 — — EP disclosed
EP-0400648-A1 Polyazo dye compounds having plural vinylsulfone type fiber reactive groups in one molecule SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 — — EP disclosed
EP-0372543-A1 Monoazo red reactive dye compound of vinylsulfone type SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-06-13 — — EP disclosed
US-4163675-A CONTAINING NAPHTHALENE DERIVATIVES PILOT INK CO., LTD. (JP) 1979-08-07 — — US disclosed
US-4029597-A AZO DYES HAVING A SULFONIC ACID OR CARBOXYL GROUP E. MERCK A. G. (DT) 1977-06-14 — — US disclosed
US-4029598-A AZO DYES HAVING A SULFONIC ACID OR CARBOXYL GROUP E. MERCK A. G. (DT) 1977-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050238679-A1 Taurine-containing preparations for improving the skin barrier CETP, CUTA, SPTLC3 ALDH1A1 592/4885MAPK1 2644/4885DUSP5 3624/4885
US-20090324656-A1 COSMETIC PREPARATIONS WITH AN ADDITIVE FROM THE BAOBAB TREE CUTA, BROX, MANBA ALDH1A1 2520/4885MAPK1 4108/4885DUSP5 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.