Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.41 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 6/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699294 | 0.94 | SMN1; SMN2 (0.42) | SMN1; SMN2NPSR1MCHR1MCHR2PKM | |
| SCHEMBL4234147 | 0.94 | CCR3 (0.38) | SMN1; SMN2NPSR1MCHR1MCHR2MET | |
| SCHEMBL4229412 | 0.92 | TAS1R3 (0.40) | SMN1; SMN2NPSR1MCHR1MCHR2PKM | |
| SCHEMBL4234061 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2NPSR1MCHR1MCHR2PKM | |
| SCHEMBL4227215 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2NPSR1MCHR1MCHR2PKM | |
| SCHEMBL4683563 | 0.90 | CCR3 (0.47) | SMN1; SMN2NPSR1MCHR1MCHR2CCR3 | |
| SCHEMBL4683015 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2NPSR1MCHR1MCHR2MET | |
| SCHEMBL4233503 | 0.89 | GPR6 (0.37) | PKMMETCCR3TAS1R3TAS1R1 | |
| SCHEMBL4238849 | 0.89 | CCR3 (0.37) | SMN1; SMN2NPSR1MCHR1MCHR2PKM | |
| SCHEMBL4745676 | 0.88 | MCHR1 (0.37) | SMN1; SMN2NPSR1MCHR1MCHR2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | claimed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | SMN1; SMN2 1538/4885NPSR1 12/4885MCHR1 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.