Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232148 | 0.92 | MCHR1 (0.40) | MCHR1MAPTLMNA | |
| SCHEMBL4233744 | 0.90 | MAPT (0.39) | MCHR1MAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL4683749 | 0.89 | LMNA (0.39) | MCHR1MAPTLMNAERBB2KMT2A | |
| SCHEMBL4229412 | 0.89 | TAS1R3 (0.40) | MCHR1SMN1; SMN2NPSR1MCHR2FLT1 | |
| SCHEMBL4683015 | 0.89 | SMN1; SMN2 (0.37) | MCHR1MAPTSMN1; SMN2NPSR1KMT2A | |
| SCHEMBL4237351 | 0.88 | LMNA (0.39) | MCHR1MAPTLMNAERBB2KMT2A | |
| SCHEMBL4233399 | 0.88 | SMN1; SMN2 (0.43) | MCHR1MAPTSMN1; SMN2NPSR1RAF1 | |
| SCHEMBL4236270 | 0.87 | MCHR1 (0.39) | MCHR1MAPTLMNAERBB2FLT1 | |
| SCHEMBL4236747 | 0.87 | TAS1R3 (0.39) | MCHR1SMN1; SMN2NPSR1MCHR2FLT1 | |
| SCHEMBL4236713 | 0.87 | MCHR1 (0.41) | MCHR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |