Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209135 | 0.99 | PDK1 (0.47) | PDK1KDM4EOPRM1SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5071191 | 0.97 | PDK1 (0.47) | PDK1KDM4EOPRM1SIGMAR1ALDH1A1 | |
| SCHEMBL4229105 | 0.92 | ADRA2A (0.48) | PDK1KDM4EALDH1A1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL7564501 | 0.83 | PDK1 (0.44) | PDK1OPRM1SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL5065542 | 0.81 | PDK1 (0.43) | PDK1KDM4EKMT2AHRH3ACHE | |
| SCHEMBL4240951 | 0.78 | ALDH1A1 (0.49) | PDK1ALDH1A1KMT2AHRH3GFER | |
| SCHEMBL5065538 | 0.78 | PDK1 (0.41) | PDK1OPRM1SIGMAR1ALDH1A1KMT2A | |
| SCHEMBL4235368 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1KMT2AHRH3GFER | |
| SCHEMBL7231255 | 0.75 | NPC1 (0.54) | KDM4EALDH1A1HRH3 | |
| SCHEMBL652110 | 0.74 | KMT2A (0.45) | PDK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | PDK1 1576/4885KDM4E 1604/4885OPRM1 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.