Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480119 | 1.00 | MAPT (0.56) | MAPTALDH1A1KDM4EGAAKMT2A | |
| Hydrochloric Acid SCHEMBL5123360 | 0.98 | MAPT (0.54) | MAPTALDH1A1KDM4EGAAKMT2A | |
| Bromide SCHEMBL11715283 | 0.98 | MAPT (0.54) | MAPTALDH1A1KDM4EGAAKMT2A | |
| Hydrochloric Acid SCHEMBL7102293 | 0.98 | MAPT (0.54) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL5506635 | 0.89 | MAPT (0.54) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL1223575 | 0.89 | KDM4E (0.53) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL6376383 | 0.86 | ALDH1A1 (0.50) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL12259328 | 0.84 | MAPT (0.53) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL5680273 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL3821707 | 0.84 | MAPT (0.53) | MAPTALDH1A1KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178809-A1 | SYNTHESIS METHOD FOR NUCIFERINE OR DERIVATIVE THEREOF, NUCIFERINE DERIVATIVE AND APPLICATION THEREOF | 华侨大学 | 2023-09-28 | — | — | WO | claimed |
| CN-109293569-B | Method for preparing formamide derivative through amine transfer reaction without participation of catalyst | 湘潭大学 | 2021-08-06 | — | — | CN | claimed |
| CN-106894074-B | A kind of processing method of automobile ECM bracket | 常州银顺汽车零部件有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-110256445-A | A kind of method of synthetic DNA-PK inhibitor STL127705 | 牡丹江师范学院 | 2019-09-20 | — | — | CN | claimed |
| CN-108148080-B | Metal organic gold (III) complex and synthesis method and application thereof | 广西师范大学 | 2019-07-09 | — | — | CN | claimed |
| CN-109851511-A | A kind of synthetic method of dobutamine hydrochloride | 浙江普利药业有限公司 | 2019-06-07 | — | — | CN | claimed |
| CN-109456268-A | The preparation of 3, the 4- dihydro-isoquinoline Alkaloid of C1 substitutions and its medical usage | 中国药科大学 | 2019-03-12 | — | — | CN | claimed |
| CN-108358913-A | A kind of green synthesis process of rotundine sulfate | 四川依科制药有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-105384650-B | A kind of 3,4 dimethoxy-phenylethylamine production technologies | 中国石油化工股份有限公司 | 2017-11-17 | — | — | CN | claimed |
| CN-106892896-A | One kind has the multifarious gold nano grain series compound in surface | 山东大学 | 2017-06-27 | — | — | CN | claimed |
| CN-102060765-A | Tetrahydroisoquinoline derivative, preparation method and application thereof | UNIV CHINA PHARMA | 2011-05-18 | — | — | CN | claimed |
| CN-101973903-A | Method for synthesizing capsaicin homolog | UNIV ZHEJIANG | 2011-02-16 | — | — | CN | claimed |
| CN-101970622-A | Lubricating composition containing polymer | LUBRIZOL CORP | 2011-02-09 | — | — | CN | claimed |
| CN-101684096-A | Novel benzoazepine compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-03-31 | — | — | CN | claimed |
| US-20090171110-A1 | PROCESS FOR PREPARING N-METHYL-3, 4-DIMETHOXYPHENYLETHYLAMINE | SICOR INC. | 2009-07-02 | — | — | US | claimed |
| CN-1396224-A | Solvent-type high-solid paint containing rheologically modified resin | CHANGZHOU ACADEMY OF PAINT CHE (CN) | 2003-02-12 | — | — | CN | claimed |
| EP-0389876-A1 | New process for the synthesis of the N-methyl-3,4-dimethoxyphenylethylamine | Alfa Chemicals Italiana S.r.l. (IT) | 1990-10-03 | — | — | EP | claimed |
| EP-0187854-A4 | SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION. | BAZZANO GAIL S | 1987-01-22 | — | — | EP | claimed |
| EP-0187854-A1 | SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION | BAZZANO, Gail S (US) | 1986-07-23 | — | — | EP | claimed |
| WO-1986000616-A1 | SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR HAIR GROWTH PROMOTION | BAZZANO GAIL SANSONE | 1986-01-30 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171110-A1 | PROCESS FOR PREPARING N-METHYL-3, 4-DIMETHOXYPHENYLETHYLAMINE | PNMT, COMT, TET3 | MAPT 3558/4885ALDH1A1 2383/4885KDM4E 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.