SCHEMBL4234652

SCHEMBL4234652

CC(C)(CN)OC(=O)CCCCCCCCCCCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 2/20 0.47
ALOX15 P16050 2/20 0.47
KMT2A Q03164 2/20 0.47
PLG P00747 1/20 0.47
THRB P10828 1/20 0.47
SLC6A2 P23975 1/20 0.47
RECQL P46063 1/20 0.47
SLC6A3 Q01959 1/20 0.47
TSHR P16473 6/20 0.44
NFKB1 P19838 2/20 0.44
PMP22 Q01453 1/20 0.44
CYP2D6 P10635 1/20 0.43
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 7/20 0.42
PPARD Q03181 7/20 0.42
PPARA Q07869 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
PTPN1 P18031 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7349183 0.86 EGLN1 (0.42) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL8756165 0.85 DGKA (0.50) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL14964640 0.85 DGKA (0.50) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL7153688 0.85 DGKA (0.50) ALDH1A1LMNAMEN1ALOX15KMT2A
Methylamine SCHEMBL8360182 0.81 TSHR (0.48) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL14964618 0.81 DGKA (0.46) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL25176741 0.80 TSHR (0.52) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL414546 0.80 TSHR (0.52) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL20897215 0.80 TSHR (0.52) ALDH1A1LMNAMEN1ALOX15KMT2A
SCHEMBL2037115 0.80 TSHR (0.52) ALDH1A1LMNAMEN1ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8816107-B2 Functionalised nanoparticles, their production and use COLOROBBIA ITALIA S.P.A. (IT) 2014-08-26 US disclosed
EP-1979365-B1 FUNCTIONALISED NANOPARTICLES, THEIR PRODUCTION AND USE COLOROBBIA ITALIANA SPA (IT) 2012-07-11 EP disclosed
US-20090054555-A1 Functionalised Nanoparticles, Their Production and Use COLOROBBIA ITALIA S.P.A. (IT) 2009-02-26 US disclosed
EP-1979365-A2 FUNCTIONALISED NANOPARTICLES, THEIR PRODUCTION AND USE Colorobbia Italia S.p.a. (IT) 2008-10-15 EP disclosed
WO-2007077240-A2 FUNCTIONALISED NANOPARTICLES, THEIR PRODUCTION AND USE COLOROBBIA ITALIA S.P.A. (IT) 2007-07-12 WO disclosed