SCHEMBL414546

SCHEMBL414546

CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.52
LMNA P02545 2/20 0.52
NFKB1 P19838 1/20 0.52
PMP22 Q01453 1/20 0.52
ALDH1A1 P00352 3/20 0.48
GPR84 Q9NQS5 8/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 7/20 0.48
PPARA Q07869 7/20 0.48
HDAC11 Q96DB2 5/20 0.48
PTPN1 P18031 3/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
FFAR1 O14842 2/20 0.48
FFAR4 Q5NUL3 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL417894 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL2183805 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL16342359 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL2037115 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL16323109 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL557403 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL25176741 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL2182221 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL20897215 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1
SCHEMBL28595399 1.00 TSHR (0.52) TSHRLMNANFKB1PMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116848-A1 Synthesis of an Intermediate and Its Use for the Preparation of GLP-1R/GIPR Agonists CARMOT THERAPEUTICS INC. (US) 2026-04-30 US claimed
US-20250188019-A1 COMPOUNDS AND METHODS FOR LIQUID PHASE SYNTHESIS ELI LILLY AND COMPANY 2025-06-12 US claimed
CN-119751308-A Method for preparing telipopeptide side chain intermediate 攀枝花学院 2025-04-04 CN claimed
CN-119661685-A Canagliflozin peptide synthesis method 杭州思诺达医药科技有限责任公司 2025-03-21 CN claimed
WO-2025052429-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TIRZEPATIDE NEULAND LABORATORIES LIMITED (IN) 2025-03-13 WO claimed
CN-119161446-B Process for preparing amylin analogues 杭州诺泰诺和生物医药科技有限公司 2025-02-14 CN claimed
CN-119161446-A Process for preparing amylin analogues 杭州诺泰诺和生物医药科技有限公司 2024-12-20 CN claimed
WO-2024134676-A1 PROCESS FOR THE PREPARATION OF TIRZEPATIDE DR. REDDY’S LABORATORIES LIMITED (IN) 2024-06-27 WO claimed
CN-117986347-A Synthesis method of canagliptin 杭州思诺达医药科技有限责任公司 2024-05-07 CN claimed
CN-117858864-A Compounds and methods for liquid phase synthesis 伊莱利利公司 2024-04-09 CN claimed
CN-117106055-A Synthesis method of telipopeptide 杭州思诺达医药科技有限责任公司 2023-11-24 CN claimed
WO-2026108124-A1 METHOD FOR PREPARING AMYLIN ANALOG 杭州诺泰诺和生物医药科技有限公司 (CN) 2026-05-28 WO disclosed
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS ELI LILLY AND CO (US) 2026-05-21 US disclosed
EP-4745153-A1 GLP-1, GIP AND GCG RECEPTOR TRIAGONIST AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-05-20 EP disclosed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN disclosed
WO-2008087189-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2008-07-24 WO disclosed
WO-2005082404-A2 GLP-2 DERIVATIVES MODIFIED BY LIPOPHILIC SUBSTITUENTS NOVO NORDISK A/S (DK) 2005-09-09 WO disclosed
EP-1554308-A2 GLUCAGON-LIKE PEPTIDE - 2 VARIANTS NOVO NORDISK A/S (DK) 2005-07-20 EP disclosed
US-20040122210-A1 GLP-2 compounds, formulations, and uses thereof NOVO NORDISK A/S (DK) 2004-06-24 US disclosed
WO-2004035624-A2 GLUCAGON - LIKE PEPTIDE - 2 VARIANTS NOVO NORDISK A/S (DK) 2004-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116848-A1 Synthesis of an Intermediate and Its Use for the Preparation of GLP-1R/GIPR Agonists GLP1R, GIPR, CCKBR TSHR 41/4885LMNA 2345/4885NFKB1 4024/4885
US-20250188019-A1 COMPOUNDS AND METHODS FOR LIQUID PHASE SYNTHESIS AQP1, CCNB1, CDK2 TSHR 4528/4885LMNA 186/4885NFKB1 1051/4885
US-20260139257-A1 PLIN1 RNAi INTERFERENCE AGENTS PLIN1, PLIN3, PLIN5 TSHR 3291/4885LMNA 70/4885NFKB1 3535/4885
US-20040122210-A1 GLP-2 compounds, formulations, and uses thereof GLP1R, GIPR, IAPP TSHR 254/4885LMNA 1526/4885NFKB1 4267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.