Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22683907 | 0.87 | GNE (0.42) | L3MBTL1HPGDKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8823572 | 0.87 | GNE (0.46) | L3MBTL1HPGDTSHRNPC1 | |
| SCHEMBL15416006 | 0.83 | SIGMAR1 (0.50) | HRH4HRH3POLBL3MBTL1HPGD | |
| SCHEMBL4351967 | 0.83 | SMN1; SMN2 (0.47) | POLBL3MBTL1HPGDKMT2ATSHR | |
| SCHEMBL15416319 | 0.83 | HPGD (0.44) | L3MBTL1HPGDKMT2AGRM5NPC1 | |
| SCHEMBL16585464 | 0.80 | CYP2C9 (0.37) | L3MBTL1HPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2186819 | 0.75 | POLB (0.51) | HRH4POLBL3MBTL1HPGDKMT2A | |
| SCHEMBL22684032 | 0.73 | SPR (0.32) | L3MBTL1 | |
| SCHEMBL13779955 | 0.72 | L3MBTL1 (0.83) | HRH4HRH3POLBL3MBTL1NPC1 | |
| SCHEMBL4279049 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |