SCHEMBL4235182

SCHEMBL4235182

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nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 2/20 0.32
CYP1A2 P05177 1/20 0.32
NFKB1 P19838 1/20 0.32
THPO P40225 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PMP22 Q01453 1/20 0.32
HK1 P19367 1/20 0.30
HK2 P52789 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393237 0.74
SCHEMBL1607814 0.74
SCHEMBL6293001 0.74
SCHEMBL26449 0.74
SCHEMBL2152717 0.74
SCHEMBL348997 0.74
SCHEMBL329683 0.74
SCHEMBL25344469 0.72 LGALS1 (0.37) ALDH1A1
SCHEMBL16751799 0.72 LGALS1 (0.37) ALDH1A1
Hydrogen Sulfide SCHEMBL1233863 0.72 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4683222-A STIMULANTS FOR IMMUNE SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1987-07-28 US claimed
US-20090182133-A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS SINGAPORE POLYTECHNIC 2009-07-16 US disclosed
US-5872111-A TOILET BAR SOAP, FACIAL BODY CLEANSER, SHAMPOO, CONDITIONER, COSMETIC,SHAVING CREAM OR LOTION, SHOWER GEL, FABRIC SOFTENING CONDITIONER, AND UNDERARM DEODORANT/ANTI-PERSPIRANT LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1999-02-16 US disclosed
US-4737488-A Immune system-stimulating N-glycosylated ureas and carbamates BAYER AKTIENGESELLSCHAFT (DE) 1988-04-12 US disclosed
US-4710491-A N-glycosylated carboxylic acid derivatives as agents for combating rheumatic diseases TROPONWERKE GMBH & CO., KG (DE) 1987-12-01 US disclosed
US-4683222-A STIMULANTS FOR IMMUNE SYSTEM BAYER AKTIENGESELLSCHAFT (DE) 1987-07-28 US disclosed
US-4680287-A N-glycosylated carboxamide derivatives as growth-promoters in livestock feeding BAYER AKTIENGESELLSCHAFT (DE) 1987-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182133-A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS SARS1, MAVS, ACE2 GRK6 431/4885CYP1A2 819/4885NFKB1 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.